Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CFTR | P13569 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28382068 | 0.79 | ALDH1A1 (0.59) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18152750 | 0.79 | ALDH1A1 (0.46) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8028315 | 0.79 | ALDH1A1 (0.46) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11020621 | 0.74 | MAPT (0.43) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3314086 | 0.73 | SMN1; SMN2 (0.62) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11361677 | 0.70 | ALDH1A1 (0.54) | MAPTALDH1A1CYP2C19RAB9APKM | |
| SCHEMBL2952899 | 0.69 | NOS2 (1.00) | NOS2CYP1A2NOD1RAB9ANPC1 | |
| SCHEMBL8395946 | 0.67 | NOS2 (0.61) | NOS2MAPTALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL5144258 | 0.67 | NOS2 (0.61) | NOS2MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL9187589 | 0.67 | NOS2 (0.61) | NOS2MAPTALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050277686-A1 | Benzimidazole compounds for regulating IgE | SIRCAR JAGADISH C | 2005-12-15 | — | — | US | disclosed |
| US-20050197375-A1 | Use of benzimidazole analogs in the treatment of cell proliferation | AVANIR PHARMACEUTICALS | 2005-09-08 | — | — | US | disclosed |
| US-6911462-B2 | Benzimidazole compounds for regulating IgE | AVANIR PHARMACEUTICALS (US) | 2005-06-28 | — | — | US | disclosed |
| US-20030100582-A1 | Benzimidazole compounds for regulating IgE | AVANIR PHARMACEUTICALS | 2003-05-29 | — | — | US | disclosed |
| US-4284713-A | SILVER, SILVER HALIDE OR BINDER IMAGE, MASKING, EXPOSURE, DEVELOPMENT, DECOMPOSITION, ALKALI HALATE OR HALITE, ETCHING | FUJI PHOTO FILM CO., LTD. (JP) | 1981-08-18 | — | — | US | disclosed |
| US-4254214-A | BLACK, REDUCTION OF COPPER SALT OR COMPLEX TO COPPER | FUJI PHOTO FILM CO., LTD. (JP) | 1981-03-03 | — | — | US | disclosed |
| US-4021247-A | Method of dispersing organic compounds useful in photography | FUJI PHOTO FILM CO., LTD. (JA) | 1977-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100582-A1 | Benzimidazole compounds for regulating IgE | FCER2, SERPINB1, BRPF3 | NOS2 2583/4885MAPT 3023/4885ALDH1A1 1209/4885 |
| US-20050277686-A1 | Benzimidazole compounds for regulating IgE | FCER2, SERPINB1, BRPF3 | NOS2 2583/4885MAPT 3023/4885ALDH1A1 1209/4885 |
| US-20050197375-A1 | Use of benzimidazole analogs in the treatment of cell proliferation | MKI67, CCNI, CDKN1A | NOS2 2985/4885MAPT 4186/4885ALDH1A1 578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.