SCHEMBL2952899

SCHEMBL2952899

Nc1nc2ccccc2n1N

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 1/20 1.00
CYP1A2 P05177 1/20 0.55
CYP2D6 P10635 1/20 0.55
HTT P42858 1/20 0.55
CXCR4 P61073 1/20 0.55
NPC1 O15118 3/20 0.52
RAB9A P51151 3/20 0.52
POLB P06746 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
TP53 P04637 1/20 0.52
TLR8 Q9NR97 3/20 0.49
NOD1 Q9Y239 3/20 0.49
CXCL8 P10145 2/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
TNF P01375 2/20 0.47
NOD2 Q9HC29 2/20 0.47
SOS1 Q07889 1/20 0.47
CSNK1A1 P48729 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2956007 0.98 NOS2 (0.96) NOS2CYP1A2CYP2D6HTTCXCR4
SCHEMBL8395946 0.76 NOS2 (0.61) NOS2CYP1A2CYP2D6HTTCXCR4
SCHEMBL9187589 0.76 NOS2 (0.61) NOS2CYP1A2CYP2D6HTTCXCR4
SCHEMBL5144258 0.76 NOS2 (0.61) NOS2HTTNPC1RAB9APOLB
SCHEMBL23038778 0.76 NOS2 (0.61) NOS2CYP1A2CYP2D6HTTCXCR4
SCHEMBL30621933 0.76 SMN1; SMN2 (0.61) NOS2CYP1A2CYP2D6HTTCXCR4
SCHEMBL22248139 0.76 NOS2 (0.61) NOS2CYP1A2CYP2D6HTTCXCR4
SCHEMBL149707 0.76 SMN1; SMN2 (0.61) NOS2CYP1A2CYP2D6HTTCXCR4
SCHEMBL18634230 0.76 NOS2 (0.61) NOS2CYP1A2CYP2D6HTTCXCR4
SCHEMBL28125888 0.76 NOS2 (0.61) NOS2CYP1A2CYP2D6HTTCXCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119736730-A Purple-black polyimide fiber and preparation method and application thereof 江苏先诺新材料科技有限公司 2025-04-01 CN claimed
CN-119709104-A Synthesis method of high-performance polyimide binder with three-dimensional reticular structure 江西洪州职业学院 2025-03-28 CN claimed
CN-119074684-A Drug delivery nano vesicle based on self-activated T cell membrane, preparation method and application 重庆医科大学附属第一医院 2024-12-06 CN claimed
CN-119061510-A Polyimide heat-insulating nanofiber with controllable cavity structure and preparation method and application thereof 陕西科技大学 2024-12-03 CN claimed
CN-119060537-A Self-lubricating wear-resistant polyphenylene sulfide-based composite material and preparation method thereof 江西聚真科技发展有限公司 2024-12-03 CN claimed
CN-118873559-A Macrophage-oncolytic virus coupling system, preparation method and application thereof in preparing antitumor drugs 国科温州研究院(温州生物材料与工程研究所) 2024-11-01 CN claimed
CN-118122270-A Composite aerogel of bimetal ZIF and biomass charcoal, and preparation method and application thereof 重庆大学 2024-06-04 CN claimed
CN-117250833-A Semiconductor chip photoresist cleaning solution, preparation method and application thereof 浙江奥首材料科技有限公司 2023-12-19 CN claimed
CN-116965422-A Permanent antibacterial microcapsule composite material and preparation method thereof 江苏海洋大学 2023-10-31 CN claimed
US-20070065443-A1 Fructoseamine 3 kinase and the formation of collagen and elastin DYNAMIS THERAPEUTICS, INC. 2007-03-22 US claimed
EP-1753861-A2 FRUCTOSEAMINE 3 KINASE AND THE FORMATION OF COLLAGEN AND ELASTIN Dynamis Therapeutics, Inc. (US) 2007-02-21 EP claimed
WO-2005079463-A2 FRUCTOSEAMINE 3 KINASE AND THE FORMATION OF COLLAGEN AND ELASTIN DYNAMIS THERAPEUTICS, INC. (US) 2005-09-01 WO claimed
US-20050159383-A1 Administering enzyme inhibitors; wrinkling and aging resistance; prevents formation Advanced Glycation End Products (AGEs) DYNAMIS THERAPEUTICS, INC. 2005-07-21 US claimed
US-20030219440-A1 3-deoxyglucosone and skin DYNAMIS THERAPEUTICS, INC. 2003-11-27 US claimed
EP-0669380-B1 Process for the preparation of azo dyes CIBA SC HOLDING AG (CH) 2001-03-28 EP claimed
US-5326779-A Method of inhibiting the advanced glycosylation of proteins using 1,2-disubstituted-benzimidazoles THE ROCKEFELLER UNIVERSITY (US) 1994-07-05 US claimed
CN-121375239-A Flame-retardant heat-insulation aluminum foil rib-sandwiched composite material and preparation method thereof 无锡奇安特保温材料有限公司 2026-01-23 CN disclosed
EP-4373811-A4 NOVEL 1,2-DIAMINOBENZIMIDAZOLE DERIVATIVE Carna Biosciences, Inc. (JP) 2025-05-21 EP disclosed
EP-0001246-A1 Preparation of 2-(3'- or 4'-aminophenyl)-5(or 6)-aminobenzimidazoles CASSELLA Aktiengesellschaft (DE) 1979-04-04 EP disclosed
US-4000135-A IRON TETRAAZANNULENES AS CATALYSTS BASF AKTIENGESELLSCHAFT (DT) 1976-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070065443-A1 Fructoseamine 3 kinase and the formation of collagen and elastin FN3K, PDXK, COLGALT1 NOS2 2809/4885CYP1A2 3833/4885CYP2D6 4398/4885
US-20030219440-A1 3-deoxyglucosone and skin DPM1, G6PD, UGGT1 NOS2 2855/4885CYP1A2 1388/4885CYP2D6 551/4885
US-20050159383-A1 Administering enzyme inhibitors; wrinkling and aging resistance; prevents formation Advanced Glycation End Products (AGEs) AGER, GLA, GALE NOS2 1372/4885CYP1A2 1462/4885CYP2D6 862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.