Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6332534 | 0.81 | MAPT (0.51) | ALDH1A1TDP1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL18152754 | 0.79 | NQO2 (0.40) | TYMSALDH1A1TDP1CYP3A4MAPT | |
| SCHEMBL1013611 | 0.74 | PARP1 (0.46) | ALDH1A1CYP3A4MAPTSMN1; SMN2KDM4E | |
| SCHEMBL3287768 | 0.74 | ALDH1A1 (0.52) | TYMSALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL6403069 | 0.72 | TDP1 (0.49) | TYMSALDH1A1TDP1CYP3A4MAPT | |
| SCHEMBL11853662 | 0.72 | MAPT (0.35) | ALDH1A1TDP1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL1201707 | 0.71 | TYMS (0.56) | TYMSALDH1A1TDP1CYP3A4MAPT | |
| SCHEMBL28030291 | 0.71 | PARP1 (0.39) | ALDH1A1CYP3A4MAPTKDM4ECYP1A2 | |
| SCHEMBL9187598 | 0.71 | MAPT (0.37) | TYMSALDH1A1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL186382 | 0.71 | MMP2 (0.58) | ALDH1A1TDP1MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050277686-A1 | Benzimidazole compounds for regulating IgE | SIRCAR JAGADISH C | 2005-12-15 | — | — | US | disclosed |
| US-20050197375-A1 | Use of benzimidazole analogs in the treatment of cell proliferation | AVANIR PHARMACEUTICALS | 2005-09-08 | — | — | US | disclosed |
| US-6911462-B2 | Benzimidazole compounds for regulating IgE | AVANIR PHARMACEUTICALS (US) | 2005-06-28 | — | — | US | disclosed |
| US-20030100582-A1 | Benzimidazole compounds for regulating IgE | AVANIR PHARMACEUTICALS | 2003-05-29 | — | — | US | disclosed |
| US-4284713-A | SILVER, SILVER HALIDE OR BINDER IMAGE, MASKING, EXPOSURE, DEVELOPMENT, DECOMPOSITION, ALKALI HALATE OR HALITE, ETCHING | FUJI PHOTO FILM CO., LTD. (JP) | 1981-08-18 | — | — | US | disclosed |
| US-4254214-A | BLACK, REDUCTION OF COPPER SALT OR COMPLEX TO COPPER | FUJI PHOTO FILM CO., LTD. (JP) | 1981-03-03 | — | — | US | disclosed |
| US-4021247-A | Method of dispersing organic compounds useful in photography | FUJI PHOTO FILM CO., LTD. (JA) | 1977-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100582-A1 | Benzimidazole compounds for regulating IgE | FCER2, SERPINB1, BRPF3 | TYMS 3551/4885ALDH1A1 1209/4885TDP1 3968/4885 |
| US-20050277686-A1 | Benzimidazole compounds for regulating IgE | FCER2, SERPINB1, BRPF3 | TYMS 3551/4885ALDH1A1 1209/4885TDP1 3968/4885 |
| US-20050197375-A1 | Use of benzimidazole analogs in the treatment of cell proliferation | MKI67, CCNI, CDKN1A | TYMS 54/4885ALDH1A1 578/4885TDP1 2445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.