Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.53 |
| ▸ | GGT1 | P19440 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6401352 | 0.89 | CFD (0.79) | CFDKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL27623501 | 0.88 | CFD (0.59) | CFDKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL16719152 | 0.87 | CFD (0.76) | CFDKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8617099 | 0.85 | MAPT (0.65) | CFDKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL31343490 | 0.84 | CFD (0.48) | CFDKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8003987 | 0.84 | CFD (0.48) | CFDKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL16719151 | 0.84 | CFD (0.88) | CFDKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL506455 | 0.83 | PPARG (0.61) | CFDKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7658382 | 0.83 | CFD (0.56) | CFDKDM4EALDH1A1PTGS1TSHR | |
| SCHEMBL9417955 | 0.82 | CYP4F2 (0.59) | CFDKDM4EHSD17B10USP2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050148554-A1 | Anti-inflammatory and anti-thrombotic compounds and their compositions | ZHANG DON (US) | 2005-07-07 | — | — | US | disclosed |
| WO-2004062598-A2 | ANTI-INFLAMMATORY AND ANTI-THROMBOTIC COMPOUNDS AND THEIR COMPOSITIONS | BETA PHARMA, INC. (US) | 2004-07-29 | — | — | WO | disclosed |
| EP-0778821-B1 | ORTHO-SUBSTITUTED AROMATIC ETHER COMPOUNDS AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS FOR PAIN RELIEF | ZENECA LTD (GB) | 1999-10-20 | — | — | EP | disclosed |
| US-5965741-A | ANTIINFLAMMATORY, ANTIPYRETIC AND ANTIDIARRHOEAL PROPERTIES | ZENECA LIMITED (GB) | 1999-10-12 | — | — | US | disclosed |
| EP-0778821-A1 | ORTHO-SUBSTITUTED AROMATIC ETHER COMPOUNDS AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS FOR PAIN RELIEF | ZENECA LIMITED (GB) | 1997-06-18 | — | — | EP | disclosed |
| WO-1996006822-A1 | ORTHO-SUBSTITUTED AROMATIC ETHER COMPOUNDS AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS FOR PAIN RELIEF | ZENECA LIMITED (GB) | 1996-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148554-A1 | Anti-inflammatory and anti-thrombotic compounds and their compositions | PTGS1, PTGS2, PTGER1 | CFD 117/4885KDM4E 3180/4885ALDH1A1 567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.