Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.36 |
| ▸ | F2RL1 | P55085 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL556899 | 0.79 | LMNA (0.39) | HIPK2F2RL1 | |
| SCHEMBL6281359 | 0.75 | AKT2 (0.49) | HIPK2ALOX15AKT2 | |
| SCHEMBL300491 | 0.71 | ALOX15 (0.41) | HIPK2F2RL1ALOX15JAK3AKT2 | |
| SCHEMBL4790799 | 0.71 | ALOX15 (0.36) | HIPK2F2RL1ALOX15JAK3AKT2 | |
| SCHEMBL6399337 | 0.71 | KDM4E (0.49) | — | |
| SCHEMBL558051 | 0.71 | HIPK2 (0.40) | HIPK2F2RL1ALOX15 | |
| SCHEMBL29952582 | 0.70 | HIPK2 (0.35) | HIPK2F2RL1JAK3 | |
| Hydrochloric Acid SCHEMBL29956711 | 0.70 | HIPK2 (0.37) | HIPK2F2RL1ALOX15JAK3AKT2 | |
| SCHEMBL311710 | 0.70 | BCHE (0.42) | HIPK2F2RL1ALOX15JAK3AKT2 | |
| Hydrochloric Acid SCHEMBL9200760 | 0.70 | ALOX15 (0.39) | HIPK2F2RL1ALOX15JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050004092-A1 | Penem derivatives and antimicrobial agent containing the same | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| EP-0757051-B1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2003-10-29 | — | — | EP | disclosed |
| US-6051569-A | 1'S, 5R, 6R-carbapenem derivatives and antimicrobial agents comprising the same | SUNTORY LIMITED (JP) | 2000-04-18 | — | — | US | disclosed |
| EP-0826687-A1 | Carbapenem derivatives and antimicrobial agents comprising the same | SUNTORY LIMITED (JP) | 1998-03-04 | — | — | EP | disclosed |
| EP-0774465-A1 | Penem derivatives and antimicrobial agents containing the same | SUNTORY LIMITED (JP) | 1997-05-21 | — | — | EP | disclosed |
| EP-0757051-A1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1997-02-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004092-A1 | Penem derivatives and antimicrobial agent containing the same | MRPL21, MRPS2, MRPS28 | HIPK2 4589/4885F2RL1 2183/4885ALOX15 2988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.