E1501

E1501

SCHEMBL6403243

CC(=O)OCc1ccccc1.OCc1ccccc1

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.85
TSHR P16473 2/20 0.54
TDP1 Q9NUW8 3/20 0.53
MAPK1 P28482 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
SLC6A2 P23975 1/20 0.53
SLC6A3 Q01959 1/20 0.53
KMT2A Q03164 1/20 0.53
HCAR2 Q8TDS4 1/20 0.53
LMNA P02545 3/20 0.50
IDH1 O75874 1/20 0.50
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
MAPT P10636 1/20 0.46
HPGD P15428 1/20 0.46
CA12 O43570 1/20 0.46
AKR1B10 O60218 1/20 0.46
AKR1B1 P15121 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
E1501 SCHEMBL8527328 0.98 ALDH1A1 (0.81) ALDH1A1TSHRTDP1MAPK1L3MBTL1
E1501 SCHEMBL901210 0.92 ALDH1A1 (1.00) ALDH1A1TSHRTDP1MAPK1L3MBTL1
E1501 SCHEMBL14031569 0.92 ALDH1A1 (1.00) ALDH1A1TSHRTDP1MAPK1L3MBTL1
E1501 SCHEMBL43745 0.92 ALDH1A1 (1.00) ALDH1A1TSHRTDP1MAPK1L3MBTL1
E1501 SCHEMBL28201296 0.92 ALDH1A1 (1.00) ALDH1A1TSHRTDP1MAPK1L3MBTL1
E1501 SCHEMBL4650267 0.90 ALDH1A1 (0.88) ALDH1A1TSHRTDP1MAPK1L3MBTL1
E1501 SCHEMBL9800714 0.90 ALDH1A1 (0.88) ALDH1A1TSHRTDP1MAPK1L3MBTL1
E1501 SCHEMBL1256238 0.90 ALDH1A1 (0.96) ALDH1A1TSHRTDP1MAPK1L3MBTL1
E1501 SCHEMBL183528 0.90 ALDH1A1 (0.96) ALDH1A1TSHRTDP1MAPK1L3MBTL1
E1501 SCHEMBL18954294 0.90 ALDH1A1 (0.96) ALDH1A1TSHRTDP1MAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050009727-A1 Laundry and cleaning compositions THE PROCTER & GAMBLE COMPANY (US) 2005-01-13 US disclosed
EP-1027419-A1 LAUNDRY COMPOSITIONS HAVING REDUCED MALODOR AND METHODS FOR PROVIDING THE SAME THE PROCTER & GAMBLE COMPANY (US) 2000-08-16 EP disclosed
WO-1999021954-A1 LAUNDRY COMPOSITIONS HAVING REDUCED MALODOR AND METHODS FOR PROVIDING THE SAME THE PROCTER & GAMBLE COMPANY (US) 1999-05-06 WO disclosed
US-4250344-A Cracking process for styrene CHEM SYSTEMS INC. (US) 1981-02-10 US disclosed