Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.43 |
| ▸ | PRKCA | P17252 | 2/20 | 0.43 |
| ▸ | GRK2 | P25098 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6407737 | 0.88 | HDAC6 (0.49) | KMT2AROCK2PRKCAGRK2SMN1; SMN2 | |
| SCHEMBL6404074 | 0.86 | SMN1; SMN2 (0.51) | L3MBTL1KMT2ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL6407783 | 0.86 | MLYCD (0.45) | KMT2AROCK2SMN1; SMN2MAPK14 | |
| SCHEMBL6409368 | 0.85 | TDP1 (0.52) | L3MBTL1KMT2ASMN1; SMN2CYP3A4KDM4E | |
| SCHEMBL6405202 | 0.85 | HSP90AA1 (0.47) | L3MBTL1KMT2AROCK2SMN1; SMN2ALDH1A1 | |
| SCHEMBL6405551 | 0.85 | KMT2A (0.41) | L3MBTL1KMT2ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL6406614 | 0.85 | NAMPT (0.48) | L3MBTL1KMT2AROCK2SMN1; SMN2CYP3A4 | |
| SCHEMBL6408033 | 0.83 | NPC1 (0.52) | KMT2AROCK2SMN1; SMN2RPS6KA5MAP4K4 | |
| SCHEMBL6403892 | 0.83 | LMNA (0.49) | KMT2ASMN1; SMN2CYP1A2CYP2D6MAPK1 | |
| SCHEMBL6402390 | 0.82 | FABP4 (0.44) | L3MBTL1KMT2ASMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | HSD17B10 191/4885L3MBTL1 607/4885KMT2A 986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.