Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.53 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265130 | 0.79 | PKM (0.56) | PKMALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL6265126 | 0.77 | PKM (0.54) | PKMALDH1A1L3MBTL1KMT2AHSD17B10 | |
| SCHEMBL6404384 | 0.75 | PKM (0.70) | PKMALDH1A1L3MBTL1KMT2AHSD17B10 | |
| SCHEMBL4204115 | 0.75 | ALDH1A1 (0.70) | PKMALDH1A1KDM4EKMT2AHSD17B10 | |
| SCHEMBL6404536 | 0.74 | ALDH1A1 (0.61) | PKMALDH1A1L3MBTL1KMT2AHSD17B10 | |
| SCHEMBL12262621 | 0.74 | PKM (0.80) | PKMALDH1A1L3MBTL1KDM4EKMT2A | |
| SCHEMBL4204903 | 0.74 | PKM (0.68) | PKMALDH1A1L3MBTL1KMT2AHSD17B10 | |
| SCHEMBL14777290 | 0.72 | KMT2A (0.59) | PKMALDH1A1L3MBTL1KMT2AHSD17B10 | |
| SCHEMBL4203150 | 0.70 | ALDH1A1 (0.64) | PKMALDH1A1L3MBTL1KMT2AHSD17B10 | |
| SCHEMBL14779109 | 0.70 | RAB9A (0.55) | PKMALDH1A1L3MBTL1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | PKM 2155/4885ALDH1A1 720/4885TDP1 288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.