Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14779109 | 0.88 | RAB9A (0.55) | ALDH1A1HPGDHTTGAANPSR1 | |
| SCHEMBL4204115 | 0.83 | ALDH1A1 (0.70) | ALDH1A1HPGDHTTGAANPSR1 | |
| SCHEMBL14777290 | 0.82 | KMT2A (0.59) | ALDH1A1HPGDHTTNPSR1HSD17B10 | |
| SCHEMBL4206304 | 0.82 | SMN1; SMN2 (0.57) | ALDH1A1HPGDHTTHSD17B10NPC1 | |
| SCHEMBL6265130 | 0.75 | PKM (0.56) | ALDH1A1HPGDHTTHSD17B10SMN1; SMN2 | |
| SCHEMBL6265126 | 0.74 | PKM (0.54) | ALDH1A1HPGDHTTNPSR1HSD17B10 | |
| SCHEMBL6403696 | 0.74 | PKM (0.55) | ALDH1A1HPGDHTTNPSR1HSD17B10 | |
| SCHEMBL4204163 | 0.73 | SMN1; SMN2 (0.57) | ALDH1A1HTTNPSR1RAB9ASMN1; SMN2 | |
| SCHEMBL6404384 | 0.72 | PKM (0.70) | ALDH1A1HPGDHTTGAANPSR1 | |
| SCHEMBL4204703 | 0.72 | SMN1; SMN2 (0.61) | ALDH1A1HTTNPSR1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | ALDH1A1 720/4885HPGD 835/4885HTT 2113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.