SCHEMBL501929

SCHEMBL501929

Cc1cc(C(C)(C)C)cc(C)c1C([O])=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.44
GABRA1 P14867 1/20 0.42
GABRB2 P47870 1/20 0.42
RXRB P28702 6/20 0.42
HTR1D P28221 2/20 0.39
HTR1B P28222 1/20 0.39
RXRA P19793 5/20 0.39
ALDH1A1 P00352 3/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
RAB9A P51151 1/20 0.39
RXRG P48443 2/20 0.38
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
HDAC1 Q13547 1/20 0.34
CYP3A4 P08684 1/20 0.34
ACHE P22303 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL501930 0.81 RXRB (0.50) POLBGABRA1GABRB2RXRBHTR1D
SCHEMBL112083 0.81 POLB (0.44) POLBGABRA1GABRB2RXRBHTR1D
SCHEMBL28034201 0.79 POLB (0.48) POLBGABRA1GABRB2RXRBHTR1D
SCHEMBL28949671 0.79 POLB (0.43) POLBGABRA1GABRB2RXRBHTR1D
SCHEMBL487289 0.77 ALDH1A1 (0.43) ALDH1A1HPGDMEN1KMT2ACYP3A4
SCHEMBL4271808 0.76 FFAR1 (0.45) POLBGABRA1GABRB2RXRBHTR1D
SCHEMBL29059825 0.76 MEN1 (0.45) POLBGABRA1GABRB2RXRBHTR1D
SCHEMBL9542624 0.76 CYP3A4 (0.53) POLBGABRA1GABRB2RXRBALDH1A1
SCHEMBL8723137 0.76 POLB (0.40) POLBGABRA1GABRB2RXRBHTR1D
SCHEMBL7185416 0.76 POLB (0.36) POLBGABRA1GABRB2RXRBHTR1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8906279-B2 Manufacturing method of polarizing plate protective film, polarizing plate protective film, polarizing plate, and liquid crystal display device KONICA MINOLTA OPTO, INC. (JP) 2014-12-09 US disclosed
US-8569405-B2 Additive mixtures for styrenic polymers BASF SE (DE) 2013-10-29 US disclosed
US-8518302-B2 Stabilization of organic materials BASF SE (DE) 2013-08-27 US disclosed
US-20120088869-A1 STABILIZATION OF ORGANIC MATERIALS GERSTER MICHELE (CH) 2012-04-12 US disclosed
US-8105504-B2 Stabilization of organic materials BASF SE (DE) 2012-01-31 US disclosed
EP-2238199-B1 ADDITIVE MIXTURES FOR STYRENIC POLYMERS BASF SE (DE) 2011-08-31 EP disclosed
EP-1786859-B1 STABILIZATION OF ORGANIC MATERIALS BASF SE (DE) 2011-06-08 EP disclosed
US-7947342-B2 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-05-24 US disclosed
US-20110071232-A1 ADDITIVE COMPOSITION FOR INCREASING THE STORAGE STABILITY OF ETHYLENICALLY UNSATURATED RESINS BASF SE (DE) 2011-03-24 US disclosed
US-20110046278-A1 ADDITIVE MIXTURES FOR STYRENIC POLYMERS BASF SE (US) 2011-02-24 US disclosed
US-5428177-A For protecting organic materials against thermal, oxidative or light-induced degradation CIBA-GEIGY CORPORATION (US) 1995-06-27 US disclosed
US-5428162-A For protecting organic materials against thermal, oxidative or light-induced degradation CIBA-GEIGY CORPORATION (US) 1995-06-27 US disclosed
EP-0648765-A1 Process for the production of 3-arylbenzofuranones CIBA-GEIGY AG (CH) 1995-04-19 EP disclosed
EP-0644190-A1 Benzofuran-2-ones as stabilizers CIBA-GEIGY AG (CH) 1995-03-22 EP disclosed
US-5369159-A Heat, oxidation and radiation resistance for polymers CIBA-GEIGY CORPORATION (US) 1994-11-29 US disclosed
US-5367008-A 3-(alkoxyphenyl)benzofuran-2-ones as stabilisers CIBA-GEIGY CORPORATION (US) 1994-11-22 US disclosed
US-5356966-A Stabilizing organic material against oxidative, thermal or light iinduced degradation CIBA-GEIGY CORPORATION (US) 1994-10-18 US disclosed
EP-0608198-A1 Cyclic diphenylacetonenitriles as stabilisers CIBA-GEIGY AG (CH) 1994-07-27 EP disclosed
EP-0591102-A1 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers CIBA-GEIGY AG (CH) 1994-04-06 EP disclosed
EP-0589839-A1 3-(Dihydrobenzofuran-5-yl)benzofuran-2-ones as stabilizers CIBA-GEIGY AG (CH) 1994-03-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120088869-A1 STABILIZATION OF ORGANIC MATERIALS LPO, AOX1, SOD1 POLB 858/4885GABRA1 3552/4885GABRB2 4501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.