Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.51 |
| ▸ | XDH | P47989 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | NHERF1 | O14745 | 3/20 | 0.49 |
| ▸ | GUSB | P08236 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.45 |
| ▸ | PYGL | P06737 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | F3 | P13726 | 1/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6399564 | 0.89 | HRH4 (0.52) | HRH4NHERF1GUSBMEN1KMT2A | |
| SCHEMBL6402611 | 0.80 | HRH4 (0.49) | HRH4NHERF1GUSBMEN1KMT2A | |
| SCHEMBL6401444 | 0.76 | PYGL (0.48) | HRH4NHERF1GUSBMEN1KMT2A | |
| SCHEMBL6398776 | 0.75 | NHERF1 (0.55) | HRH4NHERF1GUSBMEN1KMT2A | |
| SCHEMBL6398696 | 0.74 | HRH4 (0.46) | HRH4NHERF1BCAT1PYGLEGFR | |
| SCHEMBL6405492 | 0.73 | ALDH1A1 (0.50) | SMN1; SMN2GAAHRH4NHERF1MEN1 | |
| SCHEMBL6400123 | 0.73 | GUSB (0.52) | MPOXDHHRH4NHERF1GUSB | |
| SCHEMBL6400096 | 0.71 | HRH4 (0.51) | HRH4NHERF1GUSBMEN1KMT2A | |
| SCHEMBL31058769 | 0.69 | NHERF1 (0.78) | SMN1; SMN2NHERF1GUSBMEN1KMT2A | |
| SCHEMBL6407409 | 0.69 | HRH4 (0.54) | HRH4NHERF1GUSBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050054696-A1 | Indole compounds and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2005-03-10 | — | — | US | disclosed |
| EP-1452526-A1 | INDOLE COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2004-09-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050054696-A1 | Indole compounds and medicinal use thereof | IDO1, GPR119, SLC5A1 | MPO 2232/4885XDH 1508/4885SMN1; SMN2 4781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.