Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | TLR4 | O00206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6399847 | 0.84 | FFAR4 (0.33) | CHRNA7FFAR4 | |
| SCHEMBL26698382 | 0.81 | OPRM1 (0.38) | OPRM1OPRK1OPRL1TLR4 | |
| SCHEMBL20808413 | 0.77 | OPRM1 (0.35) | OPRM1OPRK1OPRL1TLR4 | |
| SCHEMBL20808415 | 0.77 | OPRM1 (0.35) | OPRM1OPRK1OPRL1TLR4 | |
| SCHEMBL20797235 | 0.77 | OPRM1 (0.35) | OPRM1OPRK1OPRL1TLR4 | |
| SCHEMBL6400747 | 0.77 | ALDH1A1 (0.38) | OPRM1OPRK1OPRL1ALDH1A1MAPT | |
| SCHEMBL6400263 | 0.76 | ALDH1A1 (0.33) | ALDH1A1MAPTHTTTLR4 | |
| SCHEMBL6397641 | 0.76 | POLB (0.42) | CHRNA7ALDH1A1MAPTHTT | |
| SCHEMBL6399843 | 0.76 | PTGDR2 (0.32) | ALDH1A1MAPTHTTTLR4 | |
| SCHEMBL14494616 | 0.76 | OPRL1 (0.36) | OPRM1OPRK1OPRL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1245660-B1 | Liquid crystal compounds having bis(trifluoromethyl)phenyl rings, liquid crystal compositions and liquid crystal display devices | CHISSO CORP (JP) | 2005-02-23 | — | — | EP | disclosed |
| US-6844032-B2 | Liquid crystal compounds having bis(trifluoromethyl) phenyl rings, liquid crystal compositions and liquid crystal display devices | CHISSO CORPORATION (JP) | 2005-01-18 | — | — | US | disclosed |
| US-20030077405-A1 | Liquid crystal compounds having bis(trifluoromethyl) phenyl rings, liquid crystal compositions and liquid crystal display devices | JNC PETROCHEMICAL CORPORATION (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1245660-A2 | Liquid crystal compounds having bis(trifluoromethyl)phenyl rings, liquid crystal compositions and liquid crystal display devices | CHISSO CORPORATION (JP) | 2002-10-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030077405-A1 | Liquid crystal compounds having bis(trifluoromethyl) phenyl rings, liquid crystal compositions and liquid crystal display devices | RCC1, KCNH2, OCIAD2 | OPRM1 795/4885OPRK1 565/4885OPRL1 1824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.