Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 6/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1509958 | 0.84 | HTR2B (0.33) | ALDH1A1MAPTHTTDRD2GRM2 | |
| SCHEMBL18134229 | 0.82 | ALDH1A1 (0.39) | ALDH1A1MAPTHTTCYP2C9DRD2 | |
| SCHEMBL8072011 | 0.82 | ALDH1A1 (0.39) | ALDH1A1MAPTHTTCYP2C9DRD2 | |
| SCHEMBL6400263 | 0.81 | ALDH1A1 (0.33) | ALDH1A1MAPTHTTTLR4 | |
| SCHEMBL17614879 | 0.81 | ALDH1A1 (0.38) | ALDH1A1MAPTHTTCYP2C9DRD2 | |
| SCHEMBL13235266 | 0.79 | OPRL1 (0.38) | ALDH1A1MAPTHTTCYP2C9DRD2 | |
| SCHEMBL13235250 | 0.79 | ALDH1A1 (0.37) | ALDH1A1MAPTHTTCYP2C9DRD2 | |
| SCHEMBL6397641 | 0.78 | POLB (0.42) | ALDH1A1MAPTHTTCYP2C9MEN1 | |
| SCHEMBL6399843 | 0.78 | PTGDR2 (0.32) | ALDH1A1MAPTHTTTLR4ACHE | |
| SCHEMBL6404087 | 0.77 | OPRM1 (0.37) | ALDH1A1MAPTHTTTLR4OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1245660-B1 | Liquid crystal compounds having bis(trifluoromethyl)phenyl rings, liquid crystal compositions and liquid crystal display devices | CHISSO CORP (JP) | 2005-02-23 | — | — | EP | disclosed |
| US-6844032-B2 | Liquid crystal compounds having bis(trifluoromethyl) phenyl rings, liquid crystal compositions and liquid crystal display devices | CHISSO CORPORATION (JP) | 2005-01-18 | — | — | US | disclosed |
| US-20030077405-A1 | Liquid crystal compounds having bis(trifluoromethyl) phenyl rings, liquid crystal compositions and liquid crystal display devices | JNC PETROCHEMICAL CORPORATION (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1245660-A2 | Liquid crystal compounds having bis(trifluoromethyl)phenyl rings, liquid crystal compositions and liquid crystal display devices | CHISSO CORPORATION (JP) | 2002-10-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030077405-A1 | Liquid crystal compounds having bis(trifluoromethyl) phenyl rings, liquid crystal compositions and liquid crystal display devices | RCC1, KCNH2, OCIAD2 | ALDH1A1 1846/4885MAPT 2799/4885HTT 4078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.