Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ALPG | P10696 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | CDC25A | P30304 | 3/20 | 0.53 |
| ▸ | CDC25B | P30305 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6411001 | 0.89 | HTT (0.67) | KMT2AMEN1HTTMAPTGAA | |
| SCHEMBL5338687 | 0.85 | MAPT (0.76) | KMT2ASMN1; SMN2MEN1HTTMAPT | |
| SCHEMBL6408144 | 0.84 | HTT (0.78) | KMT2ASMN1; SMN2MEN1HTTMAPT | |
| SCHEMBL27809458 | 0.82 | ALDH1A1 (0.63) | KMT2ASMN1; SMN2MEN1HTTMAPT | |
| SCHEMBL6403869 | 0.77 | KMT2A (0.71) | KMT2ASMN1; SMN2MEN1HTTMAPT | |
| SCHEMBL6404820 | 0.76 | KMT2A (0.76) | KMT2ASMN1; SMN2MEN1HTTMAPT | |
| SCHEMBL18292561 | 0.76 | MAPT (0.66) | MAPTALPGALDH1A1LMNACDC25A | |
| SCHEMBL29381993 | 0.76 | SMN1; SMN2 (0.65) | KMT2ASMN1; SMN2MEN1HTTMAPT | |
| SCHEMBL6405083 | 0.76 | L3MBTL1 (0.73) | KMT2ASMN1; SMN2HTTMAPTHPGD | |
| SCHEMBL29453959 | 0.75 | ALDH1A1 (0.71) | KMT2ASMN1; SMN2MEN1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | KMT2A 2263/4885SMN1; SMN2 4793/4885MEN1 3562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.