Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 13/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 13/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 13/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 13/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.66 |
| ▸ | HDAC9 | Q9UKV0 | 13/20 | 0.66 |
| ▸ | HDAC5 | Q9UQL6 | 13/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 12/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.66 |
| ▸ | NCOR1 | O75376 | 2/20 | 0.66 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | BRD4 | O60885 | 1/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.66 |
| ▸ | EGFR | P00533 | 1/20 | 0.66 |
| ▸ | LTA4H | P09960 | 1/20 | 0.66 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7806547 | 0.98 | HDAC4 (0.64) | HDAC4HDAC1HDAC7HDAC11HDAC8 | |
| Dimethylamine SCHEMBL27288007 | 0.95 | HDAC4 (0.60) | HDAC4HDAC1HDAC7HDAC11HDAC8 | |
| SCHEMBL11638411 | 0.94 | HDAC4 (0.69) | HDAC4HDAC1HDAC7HDAC11HDAC8 | |
| SCHEMBL541052 | 0.93 | HDAC4 (0.72) | HDAC4HDAC1HDAC7HDAC11HDAC8 | |
| SCHEMBL541042 | 0.93 | HDAC4 (0.72) | HDAC4HDAC1HDAC7HDAC11HDAC8 | |
| SCHEMBL19501637 | 0.89 | HDAC1 (0.58) | HDAC4HDAC1HDAC7HDAC11HDAC8 | |
| SCHEMBL376976 | 0.88 | MAPT (0.63) | HDAC4HDAC1HDAC7HDAC11HDAC8 | |
| SCHEMBL517309 | 0.88 | HDAC4 (0.81) | HDAC4HDAC1HDAC7HDAC11HDAC8 | |
| SCHEMBL6296181 | 0.88 | HDAC4 (0.75) | HDAC4HDAC1HDAC7HDAC11HDAC8 | |
| SCHEMBL137348 | 0.86 | HDAC4 (0.85) | HDAC4HDAC1HDAC7HDAC11HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113480536-A | Spirocyclic piperidone derivatives | 中国人民解放军海军军医大学 | 2021-10-08 | — | — | CN | disclosed |
| EP-3072892-B1 | PYRIDINE DERIVATIVE AND MEDICAL USE THEREOF | CHENGDU EASTON BIOPHARMACEUTICALS CO LTD (CN) | 2019-10-23 | — | — | EP | disclosed |
| US-9587266-B2 | Mutant luciferases | UNIVERSITY OF MASSACHUSETTS (US) | 2017-03-07 | — | — | US | disclosed |
| US-9587266-B2 | Mutant luciferases | UNIVERSITY OF MASSACHUSETTS (US) | 2017-03-07 | — | — | US | disclosed |
| WO-2012109470-A2 | MUTANT LUCIFERASES | UNIVERSITY OF MASSACHUSETTS (US) | 2012-08-16 | — | — | WO | disclosed |
| EP-1572608-B1 | HYDROFORMYLATION PROCESS FOR THE CONVERSION OF AN ETHYLENICALLY UNSATURATED COMPOUND TO AN ALCOHOL | SHELL INT RESEARCH (NL) | 2008-07-02 | — | — | EP | disclosed |
| US-7208606-B2 | Hydroformylation process for the conversion of an ethylenically unsaturated compound to an alcohol | SHELL OIL COMPANY (US) | 2007-04-24 | — | — | US | disclosed |
| US-20070032687-A1 | Hydroformylation process for the conversion of an ethylenically unsaturated compound to an alcohol | SHELL USA, INC. | 2007-02-08 | — | — | US | disclosed |
| US-20070032687-A1 | Hydroformylation process for the conversion of an ethylenically unsaturated compound to an alcohol | SHELL USA, INC. | 2007-02-08 | — | — | US | disclosed |
| US-20050004092-A1 | Penem derivatives and antimicrobial agent containing the same | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| EP-0757051-B1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2003-10-29 | — | — | EP | disclosed |
| EP-0757051-A1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1997-02-05 | — | — | EP | disclosed |
| US-5057524-A | Asthma, dermatitis | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004092-A1 | Penem derivatives and antimicrobial agent containing the same | MRPL21, MRPS2, MRPS28 | HDAC4 1499/4885HDAC1 122/4885HDAC7 1147/4885 |
| US-20070032687-A1 | Hydroformylation process for the conversion of an ethylenically unsaturated compound to an alcohol | ADH1C, ADH1A, ADH5 | HDAC4 3823/4885HDAC1 4763/4885HDAC7 4717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.