Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.34 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RHOA | P61586 | 1/20 | 0.33 |
| ▸ | LIG1 | P18858 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3266396 | 0.88 | CYP3A4 (0.49) | CYP3A4NPSR1PKMSMN1; SMN2TSHR | |
| SCHEMBL2420372 | 0.80 | PKM (0.47) | PKMTSHRALDH1A1HSD17B10KMT2A | |
| SCHEMBL3570137 | 0.77 | MAPT (0.45) | CYP3A4NPSR1PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL2417816 | 0.77 | ALDH1A1 (0.41) | PKMSMN1; SMN2TSHRALDH1A1HSD17B10 | |
| SCHEMBL31290664 | 0.76 | CYP3A4 (0.50) | CYP3A4NPSR1PKMSMN1; SMN2TSHR | |
| SCHEMBL28521498 | 0.76 | TDP1 (0.54) | CYP3A4NPSR1PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL29161510 | 0.75 | TSHR (0.51) | TSHRALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL8973261 | 0.75 | ALDH1A1 (0.58) | CYP3A4NPSR1PKMSMN1; SMN2TSHR | |
| SCHEMBL10385060 | 0.75 | CYP3A4 (0.67) | CYP3A4NPSR1PKMSMN1; SMN2TSHR | |
| SCHEMBL878244 | 0.75 | CYP3A4 (0.49) | CYP3A4NPSR1PKMSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100516015-C | Process for preparing alkyl 2, 2-dichloro-or dibromophenylacetates | DSM FINE CHEM AUSTRIA GMBH (AT) | 2009-07-22 | — | — | CN | disclosed |
| CN-100516015-C | Process for preparing alkyl 2, 2-dichloro-or dibromophenylacetates | DSM FINE CHEM AUSTRIA GMBH (AT) | 2009-07-22 | — | — | CN | disclosed |
| CN-1642898-A | Method for producing 2,2-dichloro or dibromo-phenyl alkyl acetates | DSM FINE CHEM AUSTRIA GMBH (AT) | 2005-07-20 | — | — | CN | disclosed |
| CN-1642898-A | Method for producing 2,2-dichloro or dibromo-phenyl alkyl acetates | DSM FINE CHEM AUSTRIA GMBH (AT) | 2005-07-20 | — | — | CN | disclosed |
| US-20050131246-A1 | Method for producing 2,2-dichloro or dibromo-phenyl alkyl acetates | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2005-06-16 | — | — | US | disclosed |
| US-20050131246-A1 | Method for producing 2,2-dichloro or dibromo-phenyl alkyl acetates | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2005-06-16 | — | — | US | disclosed |
| EP-1490322-A1 | METHOD FOR PRODUCING 2,2-DICHLORO OR DIBROMO-PHENYL ALKYL ACETATES | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003084918-A1 | METHOD FOR PRODUCING 2,2-DICHLORO OR DIBROMO-PHENYL ALKYL ACETATES | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2003-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050131246-A1 | Method for producing 2,2-dichloro or dibromo-phenyl alkyl acetates | CBR1, CBR3, ADH1C | CYP3A4 291/4885NPSR1 936/4885PKM 1447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.