Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 12/20 | 0.45 |
| ▸ | PGR | P06401 | 6/20 | 0.45 |
| ▸ | DHPS | P49366 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.38 |
| ▸ | WDR91 | A4D1P6 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6406338 | 0.89 | NR3C1 (0.42) | NR3C1PGRDHPSNR3C2 | |
| SCHEMBL6404668 | 0.79 | NR3C1 (0.59) | NR3C1PGRNR3C2 | |
| SCHEMBL4821296 | 0.78 | NR3C1 (0.74) | NR3C1PGRNR3C2 | |
| SCHEMBL6402664 | 0.76 | NR3C1 (0.47) | NR3C1PGRNR3C2 | |
| SCHEMBL5800297 | 0.75 | NR3C1 (0.48) | NR3C1PGRDHPSNR3C2 | |
| SCHEMBL4826359 | 0.72 | NR3C1 (0.59) | NR3C1PGRNR3C2 | |
| SCHEMBL4824324 | 0.70 | NR3C1 (0.74) | NR3C1PGRNR3C2 | |
| SCHEMBL1932024 | 0.69 | NR3C1 (0.42) | NR3C1PGRDHPSNR3C2 | |
| SCHEMBL14198798 | 0.69 | NR3C1 (0.57) | NR3C1PGR | |
| SCHEMBL1931080 | 0.69 | NR3C1 (0.44) | NR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050090559-A1 | Heterocyclically-substituted pentanol derivatives, process for their production and their use as anti-inflammatory agents | SCHERING AG (DE) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090559-A1 | Heterocyclically-substituted pentanol derivatives, process for their production and their use as anti-inflammatory agents | IL1B, NFKBIA, BBOX1 | NR3C1 1483/4885PGR 3289/4885DHPS 198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.