Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 17/20 | 0.42 |
| ▸ | PGR | P06401 | 6/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | DHPS | P49366 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1931080 | 0.91 | NR3C1 (0.44) | NR3C1PGRNR3C2CYP3A4 | |
| SCHEMBL1932543 | 0.84 | PPARG (0.36) | NR3C1PGR | |
| SCHEMBL3649830 | 0.70 | NR3C1 (0.69) | NR3C1PGRNR3C2 | |
| SCHEMBL1930911 | 0.69 | NR3C1 (0.38) | NR3C1PGR | |
| SCHEMBL6404402 | 0.69 | NR3C1 (0.45) | NR3C1PGRNR3C2DHPS | |
| SCHEMBL3650311 | 0.68 | NR3C1 (0.71) | NR3C1PGRNR3C2 | |
| SCHEMBL6404668 | 0.68 | NR3C1 (0.59) | NR3C1PGRNR3C2 | |
| SCHEMBL6412384 | 0.67 | NR3C1 (0.53) | NR3C1PGRNR3C2CYP3A4 | |
| SCHEMBL6585083 | 0.64 | PGR (0.68) | NR3C1PGRNR3C2 | |
| SCHEMBL3530975 | 0.64 | NR3C1 (0.51) | NR3C1PGRNR3C2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110137038-A1 | SYNTHESIS OF SELECTED STEREOISOMERS OF CERTAIN SUBSTITUTED ALCOHOLS | BAUSCH & LOMB INCORPORATED | 2011-06-09 | — | — | US | disclosed |
| EP-2086921-A2 | SYNTHESIS OF SELECTED STEREOISOMERS OF CERTAIN SUBSTITUTED ALCOHOLS | Bausch & Lomb Incorporated (US) | 2009-08-12 | — | — | EP | disclosed |
| US-20080171873-A1 | Synthesis of selected stereoisomers of certain substituted alcohols | BAUSCH & LOMB INCORPORATED | 2008-07-17 | — | — | US | disclosed |
| WO-2008060799-A2 | SYNTHESIS OF SELECTED STEREOISOMERS OF CERTAIN SUBSTITUTED ALCOHOLS | BAUSCH & LOMB INCORPORATED (US) | 2008-05-22 | — | — | WO | disclosed |
| US-20080114172-A1 | Synthesis of Selected Stereoisomers of Certain Substituted Alcohols | BAUSCH & LOMB INCORPORATED | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080114172-A1 | Synthesis of Selected Stereoisomers of Certain Substituted Alcohols | ADH1A, ADH1C, CYP2E1 | NR3C1 203/4885PGR 2372/4885NR3C2 116/4885 |
| US-20110137038-A1 | SYNTHESIS OF SELECTED STEREOISOMERS OF CERTAIN SUBSTITUTED ALCOHOLS | ADH1A, ADH1C, CYP2E1 | NR3C1 203/4885PGR 2372/4885NR3C2 116/4885 |
| US-20080171873-A1 | Synthesis of selected stereoisomers of certain substituted alcohols | ADH1A, ADH1C, ADH5 | NR3C1 74/4885PGR 3574/4885NR3C2 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.