Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LPL | P06858 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11534948 | 0.84 | ESR1 (0.58) | THRBLPLLIPGALDH1A1KDM4E | |
| SCHEMBL9338315 | 0.80 | PLK1 (0.52) | PLK1THRBL3MBTL1LPLLIPG | |
| SCHEMBL7897931 | 0.78 | SMN1; SMN2 (0.69) | PLK1THRBL3MBTL1LPLLIPG | |
| SCHEMBL5068458 | 0.78 | PLK1 (0.50) | PLK1THRBL3MBTL1LPLLIPG | |
| Hydrochloric Acid SCHEMBL7895919 | 0.78 | L3MBTL1 (0.52) | PLK1THRBL3MBTL1LPLLIPG | |
| SCHEMBL10871765 | 0.78 | PLK1 (0.55) | PLK1THRBL3MBTL1LPLLIPG | |
| SCHEMBL2773466 | 0.75 | CA1 (0.36) | SMN1; SMN2CA2 | |
| SCHEMBL142480 | 0.75 | LPL (0.62) | PLK1THRBL3MBTL1LPLLIPG | |
| SCHEMBL14218108 | 0.75 | RARB (0.49) | PLK1THRBL3MBTL1LPLLIPG | |
| SCHEMBL10874305 | 0.75 | L3MBTL1 (0.49) | PLK1THRBL3MBTL1LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1245660-B1 | Liquid crystal compounds having bis(trifluoromethyl)phenyl rings, liquid crystal compositions and liquid crystal display devices | CHISSO CORP (JP) | 2005-02-23 | — | — | EP | disclosed |
| US-6844032-B2 | Liquid crystal compounds having bis(trifluoromethyl) phenyl rings, liquid crystal compositions and liquid crystal display devices | CHISSO CORPORATION (JP) | 2005-01-18 | — | — | US | disclosed |
| EP-0893423-B1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORP (JP) | 2004-09-01 | — | — | EP | disclosed |
| US-20030077405-A1 | Liquid crystal compounds having bis(trifluoromethyl) phenyl rings, liquid crystal compositions and liquid crystal display devices | JNC PETROCHEMICAL CORPORATION (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1245660-A2 | Liquid crystal compounds having bis(trifluoromethyl)phenyl rings, liquid crystal compositions and liquid crystal display devices | CHISSO CORPORATION (JP) | 2002-10-02 | — | — | EP | disclosed |
| EP-0920405-B1 | FLUOROVINYL DERIVATIVE COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | CHISSO CORP (JP) | 2001-07-11 | — | — | EP | disclosed |
| US-6207076-B1 | HIGH ELASTIC CONSTANT RATIO, LOW VISCOSITY, WIDE NEMATIC PHASE TEMPERATURE RANGE, CHEMICAL STABILITY | CHISSO CORPORATION (JP) | 2001-03-27 | — | — | US | disclosed |
| US-6177154-B1 | MISCIBILITY; LOW IN THRESHOLD VOLTAGE, INDUCE LARGE PRETILT ANGLE, HIGH IN VOLTAGE HOLDING RATIO AND ARE LOW IN ITS DEPENDENCY ON TEMPERATURE | CHISSO CORPORATION (JP) | 2001-01-23 | — | — | US | disclosed |
| EP-0920405-A1 | FLUOROVINYL DERIVATIVE COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0893423-A1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORPORATION (JP) | 1999-01-27 | — | — | EP | disclosed |
| WO-1998008791-A1 | FLUOROVINYL DERIVATIVE COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 1998-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030077405-A1 | Liquid crystal compounds having bis(trifluoromethyl) phenyl rings, liquid crystal compositions and liquid crystal display devices | RCC1, KCNH2, OCIAD2 | PLK1 1064/4885THRB 3387/4885L3MBTL1 1069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.