Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LPL | P06858 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8679873 | 0.88 | RARB (0.53) | PLK1ALDH1A1KDM4ETHRBESR1 | |
| SCHEMBL8679652 | 0.82 | SMN1; SMN2 (0.61) | PLK1POLBALDH1A1GAAL3MBTL1 | |
| SCHEMBL28783796 | 0.80 | L3MBTL1 (0.53) | PLK1POLBCTDSP1ALDH1A1GAA | |
| SCHEMBL9338315 | 0.80 | PLK1 (0.52) | PLK1POLBCTDSP1ALDH1A1GAA | |
| SCHEMBL9098955 | 0.80 | THRB (0.55) | PLK1POLBCTDSP1ALDH1A1GAA | |
| SCHEMBL6404791 | 0.78 | PLK1 (0.50) | PLK1POLBCTDSP1ALDH1A1GAA | |
| SCHEMBL1019681 | 0.78 | PLK1 (0.60) | PLK1POLBCTDSP1ALDH1A1GAA | |
| SCHEMBL10871765 | 0.78 | PLK1 (0.55) | PLK1POLBCTDSP1ALDH1A1GAA | |
| SCHEMBL7897931 | 0.78 | SMN1; SMN2 (0.69) | PLK1POLBCTDSP1ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL7895919 | 0.78 | L3MBTL1 (0.52) | PLK1POLBCTDSP1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043299-B1 | Liquid crystalline compound, liquid crystal composition comprising the liquid crystalline compound, and liquid crystal display device using the liquid crystal composition | CHISSO CORP (JP) | 2008-10-15 | — | — | EP | disclosed |
| EP-0893423-B1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORP (JP) | 2004-09-01 | — | — | EP | disclosed |
| EP-0916639-B1 | LIQUID CRYSTAL COMPOUNDS, LIQUID CRYSTAL COMPOSITIONS CONTAINING THE COMPOUNDS, AND LIQUID CRYSTAL DISPLAY DEVICES MADE BY USING THE COMPOSITIONS | CHISSO CORP (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-6319570-B1 | LIQUID CRYSTALS AND VISUAL AIDS FILM TRANSISTOR (TFT) DISPLAY MODE DEVELOP PREFERABLE PHYSICAL PROPERTIES | CHISSO CORPORATION (JP) | 2001-11-20 | — | — | US | disclosed |
| US-6190576-B1 | MIXTURES | CHISSO CORPORATION (JP) | 2001-02-20 | — | — | US | disclosed |
| US-6177154-B1 | MISCIBILITY; LOW IN THRESHOLD VOLTAGE, INDUCE LARGE PRETILT ANGLE, HIGH IN VOLTAGE HOLDING RATIO AND ARE LOW IN ITS DEPENDENCY ON TEMPERATURE | CHISSO CORPORATION (JP) | 2001-01-23 | — | — | US | disclosed |
| EP-1043299-A2 | Liquid crystalline compound, liquid crystal composition comprising the liquid crystalline compound, and liquid crystal display device using the liquid crystal composition | CHISSO CORPORATION (JP) | 2000-10-11 | — | — | EP | disclosed |
| EP-0916639-A1 | LIQUID CRYSTAL COMPOUNDS, LIQUID CRYSTAL COMPOSITIONS CONTAINING THE COMPOUNDS, AND LIQUID CRYSTAL DISPLAY DEVICES MADE BY USING THE COMPOSITIONS | CHISSO CORPORATION (JP) | 1999-05-19 | — | — | EP | disclosed |
| EP-0893423-A1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORPORATION (JP) | 1999-01-27 | — | — | EP | disclosed |
| WO-1998037052-A1 | PREPARATION OF ARYL BROMOARYL KETONES AND CARBOXYLIC DERIVATIVES THEREOF | ALBEMARLE CORPORATION (US) | 1998-08-27 | — | — | WO | disclosed |
| EP-0041711-B1 | 6-CHLORO- OR 6-BROMO-1,2-DIHYDRO-3H-PYRROLO(1,2-A)-PYRROLE-1-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF, PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYNTEX (U.S.A.) INC. (US) | 1985-04-17 | — | — | EP | disclosed |
| US-4410534-A | 3-Substituted-5,6,7,8-tetrahydropyrrolo[1,2-a]-pyridine-and 6,7,8,9-tetrahydro-5H-pyrrolo[1,2-a]-azepine carboxylic acid derivatives useful as blood platelet aggregation inhibitors | SYNTEX (U.S.A.) INC. (US) | 1983-10-18 | — | — | US | disclosed |
| US-4344943-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1982-08-17 | — | — | US | disclosed |
| EP-0041711-A1 | 6-Chloro- or 6-bromo-1,2-dihydro-3H-pyrrolo(1,2-a)-pyrrole-1-carboxylic acids and derivatives thereof, process for their production and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1981-12-16 | — | — | EP | disclosed |
| US-4232038-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, AND MUSCLE RELAXANTS | SYNTEX (U.S.A.) INC. (US) | 1980-11-04 | — | — | US | disclosed |