Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | RGS12 | O14924 | 2/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.56 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6403470 | 0.87 | HTT (0.70) | MAPTKMT2AGAAALDH1A1POLB | |
| SCHEMBL13856843 | 0.84 | MAPT (0.65) | MAPTKMT2AGAARGS12ALDH1A1 | |
| SCHEMBL14907898 | 0.82 | ALDH1A1 (0.75) | MAPTKMT2AGAARXFP1ALDH1A1 | |
| SCHEMBL1514509 | 0.82 | KDM4E (0.66) | MAPTKMT2AGAARGS12ALDH1A1 | |
| SCHEMBL6408638 | 0.81 | TP53 (0.74) | MAPTKMT2AGAARGS12RXFP1 | |
| SCHEMBL4203841 | 0.80 | SENP1 (0.74) | MAPTKMT2AGAARXFP1ALDH1A1 | |
| SCHEMBL18540561 | 0.80 | ALDH1A1 (0.75) | MAPTKMT2AGAARXFP1ALDH1A1 | |
| SCHEMBL4209228 | 0.79 | THRB (0.65) | MAPTKMT2ARXFP1ALDH1A1TP53 | |
| SCHEMBL4206188 | 0.77 | MAPT (0.73) | MAPTKMT2AGAARXFP1ALDH1A1 | |
| SCHEMBL17213042 | 0.77 | ALDH1A1 (0.70) | MAPTKMT2AGAARXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | MAPT 2111/4885KMT2A 2263/4885GAA 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.