Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.74 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.71 |
| ▸ | ATM | Q13315 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 6/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | RGS12 | O14924 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4203841 | 0.92 | SENP1 (0.74) | TP53SENP1L3MBTL1MAPTRXFP1 | |
| SCHEMBL4209228 | 0.84 | THRB (0.65) | TP53SENP1L3MBTL1MAPTRXFP1 | |
| SCHEMBL29552362 | 0.83 | SENP1 (0.72) | TP53SENP1L3MBTL1MAPTKMT2A | |
| SCHEMBL14907898 | 0.83 | ALDH1A1 (0.75) | TP53SENP1MAPTPOLBRXFP1 | |
| SCHEMBL18540561 | 0.83 | ALDH1A1 (0.75) | TP53L3MBTL1MAPTPOLBRXFP1 | |
| SCHEMBL4206188 | 0.82 | MAPT (0.73) | TP53MAPTPOLBRXFP1KMT2A | |
| SCHEMBL4204602 | 0.81 | ALOX15 (0.81) | TP53MAPTPOLBRXFP1KMT2A | |
| SCHEMBL6405166 | 0.81 | MAPT (0.71) | TP53SENP1MAPTPOLBRXFP1 | |
| SCHEMBL30365924 | 0.81 | TP53 (0.77) | TP53SENP1MAPTPOLBKMT2A | |
| SCHEMBL15983400 | 0.81 | L3MBTL1 (0.67) | TP53SENP1L3MBTL1ATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | TP53 1524/4885SENP1 1979/4885L3MBTL1 2749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.