Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | APLNR | P35414 | 4/20 | 0.57 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.53 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20514201 | 0.86 | APLNR (0.73) | APLNR | |
| SCHEMBL18559219 | 0.81 | TDP1 (0.51) | ALDH1A1SMN1; SMN2TSHRGAAHSD17B10 | |
| SCHEMBL17295000 | 0.80 | AVPR2 (0.60) | ALDH1A1SMN1; SMN2AVPR2AVPR1ADRD2 | |
| SCHEMBL6407017 | 0.78 | MEN1 (0.60) | ALDH1A1SMN1; SMN2APLNRTSHRKDM4E | |
| SCHEMBL10432252 | 0.76 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2APLNRAVPR1AHTT | |
| SCHEMBL18254537 | 0.75 | APLNR (0.76) | APLNR | |
| SCHEMBL931766 | 0.74 | TSHR (0.53) | ALDH1A1AVPR2AVPR1ATSHRHPGD | |
| SCHEMBL6405947 | 0.73 | DRD2 (0.53) | ALDH1A1SMN1; SMN2HTTDRD2DRD3 | |
| SCHEMBL18246050 | 0.73 | APLNR (0.73) | APLNR | |
| SCHEMBL17295029 | 0.73 | APLNR (0.56) | ALDH1A1APLNRAVPR2AVPR1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | ALDH1A1 720/4885SMN1; SMN2 4793/4885APLNR 4836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.