Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.71 |
| ▸ | RXRB | P28702 | 2/20 | 0.71 |
| ▸ | RXRG | P48443 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404554 | 0.89 | TDP1 (0.70) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6404082 | 0.83 | RXRA (0.74) | RXRARXRBRXRGKDM4ENPC1 | |
| SCHEMBL6410816 | 0.82 | RXRA (0.74) | RXRARXRBRXRGKDM4ENPC1 | |
| SCHEMBL6403407 | 0.80 | PKM (0.74) | ALDH1A1KMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL20248141 | 0.74 | SIRT2 (0.73) | RXRARXRBRXRGKDM4EALDH1A1 | |
| SCHEMBL11887417 | 0.73 | KMT2A (0.80) | NPC1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10016348 | 0.73 | SMN1; SMN2 (0.80) | NPC1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL29558785 | 0.72 | TSHR (0.66) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL23075079 | 0.71 | TDP1 (0.78) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6405241 | 0.71 | L3MBTL1 (0.84) | ALDH1A1KMT2AMEN1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | RXRA 2854/4885RXRB 2513/4885RXRG 2497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.