Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | GLA | P06280 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | RECQL | P46063 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16491233 | 0.86 | SMN1; SMN2 (1.00) | SMN1; SMN2GLATSHRTP53RECQL | |
| SCHEMBL18559039 | 0.83 | TSHR (0.76) | SMN1; SMN2GLATSHRTP53RECQL | |
| SCHEMBL15986564 | 0.81 | TSHR (0.84) | SMN1; SMN2GLATSHRTP53RECQL | |
| SCHEMBL15986516 | 0.81 | LMNA (0.79) | SMN1; SMN2TSHRTP53RECQLPOLB | |
| SCHEMBL18559209 | 0.79 | TSHR (1.00) | SMN1; SMN2GLATSHRTP53RECQL | |
| SCHEMBL18559294 | 0.79 | TSHR (0.88) | SMN1; SMN2GLATSHRTP53RECQL | |
| SCHEMBL18559194 | 0.78 | TSHR (0.81) | SMN1; SMN2GLATSHRTP53RECQL | |
| SCHEMBL18559212 | 0.76 | L3MBTL1 (0.85) | SMN1; SMN2GLATSHRTP53RECQL | |
| SCHEMBL14970814 | 0.76 | SMN1; SMN2 (0.71) | SMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL15983725 | 0.74 | PKM (0.65) | SMN1; SMN2TSHRPOLBMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | SMN1; SMN2 4793/4885GLA 983/4885TSHR 3470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.