Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | GLA | P06280 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 6/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6405909 | 0.86 | SMN1; SMN2 (0.74) | SMN1; SMN2GLATSHRALDH1A1LMNA | |
| SCHEMBL15986586 | 0.82 | TSHR (1.00) | SMN1; SMN2GLATSHRALDH1A1LMNA | |
| SCHEMBL15986564 | 0.76 | TSHR (0.84) | SMN1; SMN2GLATSHRALDH1A1LMNA | |
| SCHEMBL18559212 | 0.76 | L3MBTL1 (0.85) | SMN1; SMN2GLATSHRALDH1A1LMNA | |
| SCHEMBL18559367 | 0.75 | CYP1A2 (1.00) | SMN1; SMN2GLATSHRALDH1A1LMNA | |
| SCHEMBL4203301 | 0.75 | CYP1A2 (0.77) | SMN1; SMN2GLATSHRALDH1A1LMNA | |
| SCHEMBL18559039 | 0.74 | TSHR (0.76) | SMN1; SMN2GLATSHRALDH1A1LMNA | |
| SCHEMBL18559294 | 0.74 | TSHR (0.88) | SMN1; SMN2GLATSHRALDH1A1LMNA | |
| SCHEMBL18559209 | 0.74 | TSHR (1.00) | SMN1; SMN2GLATSHRALDH1A1LMNA | |
| SCHEMBL15986535 | 0.74 | TSHR (1.00) | SMN1; SMN2GLATSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230136150-A1 | Compositions for Inhibition of Insect Sensing | UNIV VANDERBILT (US) | 2023-05-04 | — | — | US | disclosed |
| US-20210219551-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2021-07-22 | — | — | US | disclosed |
| US-10813355-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2020-10-27 | — | — | US | disclosed |
| US-20190075798-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2019-03-14 | — | — | US | disclosed |
| US-10188105-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2019-01-29 | — | — | US | disclosed |
| US-9598395-B2 | Premature-termination-codons readthrough compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-03-21 | — | — | US | disclosed |
| US-9578881-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2017-02-28 | — | — | US | disclosed |
| US-20150051251-A1 | PREMATURE-TERMINATION-CODONS READTHROUGH COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230136150-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | SMN1; SMN2 4423/4885GLA 4600/4885TSHR 2971/4885 |
| US-10813355-B2 | Compositions for inhibition of insect sensing | OR51E2, TRPA1, OR10J3 | SMN1; SMN2 4355/4885GLA 4672/4885TSHR 3088/4885 |
| US-20150051251-A1 | PREMATURE-TERMINATION-CODONS READTHROUGH COMPOUNDS | UPF1, NUDT21, RNGTT | SMN1; SMN2 563/4885GLA 1649/4885TSHR 1606/4885 |
| US-20210219551-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | SMN1; SMN2 4423/4885GLA 4600/4885TSHR 2971/4885 |
| US-10188105-B2 | Compositions for inhibition of insect sensing | OR51E2, TRPA1, OR10J3 | SMN1; SMN2 4404/4885GLA 4687/4885TSHR 2976/4885 |
| US-20190075798-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | SMN1; SMN2 4355/4885GLA 4672/4885TSHR 3088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.