Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 6/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6406749 | 1.00 | AVPR1A (0.48) | AVPR1AHDAC4CNR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6405987 | 0.84 | AVPR1A (0.53) | AVPR1AHDAC4SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL4966313 | 0.81 | HDAC4 (0.49) | AVPR1AHDAC4SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL4963772 | 0.80 | TRPA1 (0.53) | AVPR1AHDAC4SMN1; SMN2ALDH1A1KCNH2 | |
| SCHEMBL6405064 | 0.80 | AVPR1A (0.49) | AVPR1AHDAC4SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL6406056 | 0.79 | HDAC4 (0.47) | AVPR1AHDAC4SMN1; SMN2ALDH1A1KCNH2 | |
| SCHEMBL5049115 | 0.77 | AVPR1A (0.57) | AVPR1AHDAC4SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL6407406 | 0.75 | CYP3A4 (0.47) | AVPR1AHDAC4SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL4971409 | 0.74 | HDAC4 (0.47) | AVPR1AHDAC4SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL6410915 | 0.73 | ALDH1A1 (0.62) | AVPR1AHDAC4SMN1; SMN2ALDH1A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288338-A1 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION | 2005-12-29 | — | — | US | claimed |
| US-20050288338-A1 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288338-A1 | Amido compounds and their use as pharmaceuticals | HSD11B1, CYP11B1, HSD11B2 | AVPR1A 57/4885HDAC4 1710/4885CNR1 430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.