Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | TDO2 | P48775 | 9/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4628521 | 0.90 | NR3C1 (0.39) | TDO2NR3C1PGR | |
| SCHEMBL4735534 | 0.78 | NR3C1 (0.47) | NR3C1PGR | |
| SCHEMBL6408234 | 0.77 | NR3C1 (0.38) | NR3C1PGR | |
| SCHEMBL5802087 | 0.77 | NR3C1 (0.40) | TDO2NR3C1PGR | |
| SCHEMBL6405691 | 0.75 | NR3C1 (0.41) | NR3C1PGR | |
| SCHEMBL4629928 | 0.73 | NR3C1 (0.54) | NR3C1PGR | |
| SCHEMBL6404388 | 0.73 | NR3C1 (0.36) | NR3C1PGR | |
| SCHEMBL6406146 | 0.73 | NR3C1 (0.39) | IDO1TDO2NR3C1PGR | |
| SCHEMBL4628810 | 0.72 | NR3C1 (0.46) | NR3C1PGR | |
| SCHEMBL4630426 | 0.71 | NR3C1 (0.42) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050090559-A1 | Heterocyclically-substituted pentanol derivatives, process for their production and their use as anti-inflammatory agents | SCHERING AG (DE) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090559-A1 | Heterocyclically-substituted pentanol derivatives, process for their production and their use as anti-inflammatory agents | IL1B, NFKBIA, BBOX1 | IDO1 16/4885TDO2 266/4885NR3C1 1483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.