Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6407001 | 1.00 | GPR119 (0.47) | GPR119FAAHRECQLNR1H2 | |
| SCHEMBL6150245 | 0.85 | GPR119 (0.51) | GPR119 | |
| SCHEMBL6156324 | 0.84 | HPGD (0.58) | GPR119 | |
| SCHEMBL6156540 | 0.83 | GPR119 (0.53) | GPR119 | |
| SCHEMBL4089937 | 0.82 | USP2 (0.41) | RECQLNR1H2 | |
| SCHEMBL23536215 | 0.82 | GPR119 (0.46) | GPR119FAAHRECQLNR1H2 | |
| SCHEMBL6156705 | 0.82 | GPR119 (0.53) | GPR119 | |
| SCHEMBL5192061 | 0.81 | GPR119 (0.51) | GPR119 | |
| SCHEMBL72535 | 0.81 | NR1H2 (0.51) | RECQLNR1H2 | |
| SCHEMBL23536024 | 0.81 | RECQL (0.46) | GPR119FAAHRECQLNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143391-A1 | Heterocyclic amides with alpha-4 integrin antagonist activity | J. Uriach Y Compañia S.A. (ES) | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143391-A1 | Heterocyclic amides with alpha-4 integrin antagonist activity | ITGB4, ITGA4, ITGA1 | GPR119 789/4885FAAH 1729/4885RECQL 4751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.