SCHEMBL6407153

SCHEMBL6407153

CC1C(COC(c2ccccc2)(c2ccccc2)c2ccccc2)C1C(=O)OC1CCCCC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP7 O15540 1/20 0.47
FABP5 Q01469 1/20 0.47
CHRM3 P20309 11/20 0.39
CHRM2 P08172 8/20 0.39
CHRM1 P11229 5/20 0.39
CHRM4 P08173 3/20 0.39
CHRM5 P08912 3/20 0.39
KCNH2 Q12809 3/20 0.37
HRH1 P35367 2/20 0.37
SLC6A1 P30531 1/20 0.37
MLNR O43193 1/20 0.37
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
OPRM1 P35372 1/20 0.37
DRD3 P35462 1/20 0.37
OPRK1 P41145 1/20 0.37
HTR2B P41595 1/20 0.37
SLC6A3 Q01959 1/20 0.37
CACNA1C Q13936 1/20 0.37
CYP19A1 P11511 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6407574 0.93 SLC6A11 (0.45) FABP7FABP5CHRM3CHRM2CHRM1
SCHEMBL6408948 0.93 SLC6A11 (0.45) FABP7FABP5CHRM3CHRM2CHRM1
SCHEMBL6409654 0.87 SLC6A11 (0.41) FABP7FABP5SLC6A1SLC6A3SLC6A4
SCHEMBL6414832 0.81 POLB (0.41) SLC6A1SLC6A3LMNACYP2D6CYP2C19
SCHEMBL6410593 0.80 FABP7 (0.48) FABP7FABP5CHRM3CHRM2CHRM1
SCHEMBL6415870 0.79 SLC6A1 (0.39) FABP7SLC6A1OPRM1DRD3CYP2C19
SCHEMBL6408113 0.79 FABP7 (0.44) FABP7FABP5CHRM3CHRM2CHRM1
SCHEMBL6409527 0.79 TSHR (0.40) FABP7CYP2D6CYP2C19
SCHEMBL6407053 0.79 CYP2C19 (0.37) SLC6A1CYP2C19
SCHEMBL6411610 0.79 FABP7 (0.47) FABP7FABP5CHRM3CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids SUMITOMO CHEMICAL COMPAY LIMTED (JP) 2005-12-29 US disclosed
EP-1538141-A1 PROCESS FOR PRODUCTION OF 2-(HYDROXYMETHYL)CYCLO- PROPANECARBOXYLIC ACIDS Sumitomo Chemical Company, Limited (JP) 2005-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids GRHPR, PCCA, C5 FABP7 4846/4885FABP5 4727/4885CHRM3 2880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.