Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LSS | P48449 | 1/20 | 0.44 |
| ▸ | RHOC | P08134 | 1/20 | 0.44 |
| ▸ | RHOA | P61586 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6406614 | 0.87 | NAMPT (0.48) | POLBSMN1; SMN2LMNAKMT2AMAPK14 | |
| SCHEMBL6404399 | 0.86 | HSD17B10 (0.48) | SMN1; SMN2KMT2AMAPK14ROCK2 | |
| SCHEMBL6404074 | 0.86 | SMN1; SMN2 (0.51) | POLBSMN1; SMN2LMNAKMT2AMAPK14 | |
| SCHEMBL6405551 | 0.85 | KMT2A (0.41) | POLBSMN1; SMN2KMT2AEPHX2 | |
| SCHEMBL6409368 | 0.85 | TDP1 (0.52) | POLBSMN1; SMN2LMNAKMT2AMAPK14 | |
| SCHEMBL6405202 | 0.85 | HSP90AA1 (0.47) | POLBSMN1; SMN2KMT2AROCK2 | |
| SCHEMBL6403173 | 0.84 | NPC1 (0.46) | MLYCDPOLBLSSSMN1; SMN2EPHX2 | |
| SCHEMBL6407737 | 0.84 | HDAC6 (0.49) | POLBSMN1; SMN2KMT2AHDAC1ROCK2 | |
| SCHEMBL6408033 | 0.82 | NPC1 (0.52) | POLBSMN1; SMN2LMNAKMT2AHDAC1 | |
| SCHEMBL6403892 | 0.82 | LMNA (0.49) | SMN1; SMN2LMNAKMT2AEPHX2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | MLYCD 2123/4885POLB 3713/4885LSS 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.