Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 10/20 | 0.51 |
| ▸ | ITK | Q08881 | 3/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.45 |
| ▸ | CLK2 | P49760 | 2/20 | 0.45 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.45 |
| ▸ | MARK3 | P27448 | 1/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | NEK4 | P51957 | 1/20 | 0.45 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.45 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4979124 | 0.82 | IRAK4 (0.53) | IRAK4MAPTCNR2KMT2AOPRM1 | |
| SCHEMBL209281 | 0.79 | ALDH1A1 (0.54) | MAPTKMT2AALDH1A1PKM | |
| SCHEMBL8265180 | 0.71 | HTR7 (0.56) | MAPTKMT2A | |
| SCHEMBL6231609 | 0.70 | KMT2A (0.51) | IRAK4ITKMAP4K4CSNK1DCLK2 | |
| SCHEMBL6258346 | 0.70 | ALDH1A1 (0.52) | IRAK4IRAK1MAPTKMT2AALDH1A1 | |
| SCHEMBL3781560 | 0.69 | GLS (0.53) | IRAK4MAPTCNR2KMT2A | |
| SCHEMBL6231431 | 0.69 | KDM4E (0.43) | MAPTKMT2AALDH1A1PKM | |
| SCHEMBL17434602 | 0.68 | PARG (0.60) | MAPTCNR2KMT2AADORA2AALDH1A1 | |
| SCHEMBL17434506 | 0.68 | CYP1A2 (0.57) | MAPTCNR2KMT2AALDH1A1 | |
| SCHEMBL23045545 | 0.68 | MAPT (0.48) | MAPTKMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004092181-A9 | HETEROCYCLIC MCHR1 ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2005-01-27 | — | — | WO | disclosed |