Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4764093 | 0.76 | KDM4E (0.35) | HCAR2TSHRRAB9ANPC1KDM4E | |
| SCHEMBL6790953 | 0.75 | ALDH1A1 (0.41) | TSHRRAB9ANPC1KDM4ETP53 | |
| SCHEMBL6789320 | 0.75 | ACACB (0.41) | TSHRRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL8890442 | 0.75 | GABRP (0.38) | HPGDKMT2ACYP1A2GABRPGABRD | |
| SCHEMBL285550 | 0.74 | GRM5 (0.43) | ATMRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL29756638 | 0.74 | GRM5 (0.43) | ATMRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL14127796 | 0.73 | RAB9A (0.40) | L3MBTL1RAB9ANPC1 | |
| SCHEMBL31017536 | 0.72 | PTPN11 (0.48) | L3MBTL1RAB9ANPC1EGFR | |
| SCHEMBL6789803 | 0.72 | PTPN11 (0.48) | L3MBTL1RAB9ANPC1EGFR | |
| SCHEMBL4764055 | 0.72 | GBA1 (0.43) | RAB9ANPC1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050101593-A1 | Phosphoric acid salt of an integrin receptor antagonist | MEISSNER ROBERT S (US) | 2005-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101593-A1 | Phosphoric acid salt of an integrin receptor antagonist | ITGA5, ITGAL, ITGA2 | HPGD 2852/4885HCAR2 108/4885KMT2A 4230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.