SCHEMBL6408765

SCHEMBL6408765

O=C(OC1CCCCC1)C1CC1COCc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FABP7 O15540 1/20 0.45
FABP5 Q01469 1/20 0.45
CHRM2 P08172 2/20 0.45
CHRM4 P08173 2/20 0.45
CHRM5 P08912 2/20 0.45
CHRM1 P11229 2/20 0.45
CHRM3 P20309 2/20 0.45
FFAR4 Q5NUL3 2/20 0.41
SGMS2 Q8NHU3 1/20 0.41
AGTR2 P50052 1/20 0.40
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP19A1 P11511 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6406983 0.93 EPHX1 (0.47) FABP7FABP5CHRM2CHRM4CHRM5
SCHEMBL6414684 0.87 CACNA1B (0.44) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL6407549 0.79 CPB1 (0.51) FFAR4AGTR2ALDH1A1TSHR
SCHEMBL17407791 0.79 CPB1 (0.51) FFAR4AGTR2ALDH1A1TSHR
SCHEMBL6410593 0.79 FABP7 (0.48) FABP7FABP5CHRM2CHRM4CHRM5
SCHEMBL5447182 0.78 FFAR4 (0.57) FFAR4AGTR2ALDH1A1TSHR
SCHEMBL17391191 0.78 FFAR4 (0.57) FFAR4AGTR2ALDH1A1TSHR
SCHEMBL5924916 0.78 FFAR4 (0.57) FFAR4AGTR2ALDH1A1TSHR
SCHEMBL29018749 0.78 FFAR4 (0.57) FFAR4AGTR2ALDH1A1TSHR
SCHEMBL29188003 0.78 FFAR4 (0.57) FFAR4AGTR2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids SUMITOMO CHEMICAL COMPAY LIMTED (JP) 2005-12-29 US disclosed
CN-1681767-A Method for manufacturing 2-(hydroxymethyl) cyclopropane carboxylic acid compound SUMITOMO CHEMICAL CO (JP) 2005-10-12 CN disclosed
EP-1538141-A1 PROCESS FOR PRODUCTION OF 2-(HYDROXYMETHYL)CYCLO- PROPANECARBOXYLIC ACIDS Sumitomo Chemical Company, Limited (JP) 2005-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids GRHPR, PCCA, C5 FABP7 4846/4885FABP5 4727/4885CHRM2 1364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.