SCHEMBL6406983

SCHEMBL6406983

O=C(OC1CCCCC1)C1CC1COCc1ccc(-c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.47
FFAR4 Q5NUL3 3/20 0.45
NAAA Q02083 1/20 0.43
FAAH O00519 1/20 0.42
MGLL Q99685 1/20 0.42
CHRM2 P08172 3/20 0.42
CHRM4 P08173 3/20 0.42
CHRM5 P08912 3/20 0.42
CHRM1 P11229 3/20 0.42
CHRM3 P20309 3/20 0.42
FABP7 O15540 1/20 0.41
FABP5 Q01469 1/20 0.41
ABHD6 Q9BV23 1/20 0.41
DAGLA Q9Y4D2 1/20 0.41
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
KMT2A Q03164 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
ADAMTS4 O75173 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6408765 0.93 FABP7 (0.45) FFAR4CHRM2CHRM4CHRM5CHRM1
SCHEMBL6414684 0.85 CACNA1B (0.44) FFAR4CHRM2CHRM4CHRM5CHRM1
SCHEMBL6406962 0.81 FFAR4 (0.49) EPHX1FFAR4NAAAALDH1A1KMT2A
SCHEMBL6409645 0.81 FFAR4 (0.62) EPHX1FFAR4NAAA
SCHEMBL6408048 0.81 EPHX1 (0.45) EPHX1NAAAFAAHMGLLCHRM2
SCHEMBL6414745 0.80 EPHX1 (0.44) EPHX1NAAAFAAHMGLLCHRM2
SCHEMBL6412514 0.79 CA12 (0.48) EPHX1FFAR4NAAA
SCHEMBL6407743 0.78 FFAR4 (0.47) EPHX1FFAR4NAAA
SCHEMBL6406431 0.76 ALDH1A1 (0.47) FFAR4MEN1ALDH1A1KMT2A
SCHEMBL27624969 0.75 FFAR4 (0.44) EPHX1FFAR4NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids SUMITOMO CHEMICAL COMPAY LIMTED (JP) 2005-12-29 US disclosed
CN-1681767-A Method for manufacturing 2-(hydroxymethyl) cyclopropane carboxylic acid compound SUMITOMO CHEMICAL CO (JP) 2005-10-12 CN disclosed
EP-1538141-A1 PROCESS FOR PRODUCTION OF 2-(HYDROXYMETHYL)CYCLO- PROPANECARBOXYLIC ACIDS Sumitomo Chemical Company, Limited (JP) 2005-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids GRHPR, PCCA, C5 EPHX1 1885/4885FFAR4 2429/4885NAAA 1503/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.