Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 5/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 7/20 | 0.32 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27623279 | 0.81 | HTR3A (0.40) | HTR3AMGLLDCTPP1TP53MAPT | |
| SCHEMBL2960897 | 0.73 | KAT2B (0.38) | — | |
| SCHEMBL13217366 | 0.71 | HTR3A (0.44) | HTR3ADCTPP1 | |
| SCHEMBL6417245 | 0.71 | DPP4 (0.34) | — | |
| SCHEMBL27623316 | 0.68 | HTR2B (0.41) | — | |
| SCHEMBL29252729 | 0.66 | AGTR2 (0.48) | — | |
| SCHEMBL6889140 | 0.65 | ALDH1A1 (0.43) | HTR3AMGLLMAPT | |
| SCHEMBL22519008 | 0.65 | CHRM1 (0.46) | SLC6A9 | |
| SCHEMBL4749555 | 0.65 | KDM4E (0.42) | SLC6A9 | |
| SCHEMBL4532377 | 0.65 | HTR3A (0.53) | HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1514552-A1 | NOVEL FUSED IMIDAZOLE DERIVATIVE | Eisai Co., Ltd. (JP) | 2005-03-16 | — | — | EP | disclosed |