Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 7/20 | 0.31 |
| ▸ | BPTF | Q12830 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 2/20 | 0.31 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13217402 | 0.82 | DPP4 (0.47) | DPP4MEN1KMT2APIM1PIM3 | |
| SCHEMBL2960897 | 0.79 | KAT2B (0.38) | SPRKAT2BBPTFBTK | |
| SCHEMBL28566782 | 0.73 | PIM2 (0.40) | PIM1PIM3PIM2 | |
| SCHEMBL27623279 | 0.72 | HTR3A (0.40) | — | |
| SCHEMBL13217366 | 0.71 | HTR3A (0.44) | MEN1KMT2APIM1ADORA1 | |
| SCHEMBL6408912 | 0.71 | SLC6A9 (0.34) | — | |
| SCHEMBL28403316 | 0.67 | LMNA (0.54) | MEN1KMT2A | |
| SCHEMBL28403318 | 0.67 | LMNA (0.54) | MEN1KMT2A | |
| SCHEMBL25376365 | 0.65 | HRH3 (0.49) | — | |
| SCHEMBL14044476 | 0.65 | DPP4 (0.59) | DPP4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1700911-A | Combination drug | EISAI CO LTD (JP) | 2005-11-23 | — | — | CN | disclosed |
| EP-1514552-A1 | NOVEL FUSED IMIDAZOLE DERIVATIVE | Eisai Co., Ltd. (JP) | 2005-03-16 | — | — | EP | disclosed |