Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL29562689 | 0.92 | KMT2A (0.51) | TDP1LMNAALDH1A1HPGDGAA | |
| SCHEMBL6415536 | 0.91 | SMN1; SMN2 (0.56) | TDP1LMNAALDH1A1HPGDGAA | |
| SCHEMBL6408734 | 0.91 | SMN1; SMN2 (0.56) | TDP1LMNAALDH1A1HPGDGAA | |
| SCHEMBL6407958 | 0.91 | TDP1 (0.62) | TDP1LMNAALDH1A1HPGDGAA | |
| SCHEMBL6414886 | 0.89 | TDP1 (0.65) | TDP1LMNAALDH1A1HPGDGAA | |
| SCHEMBL6407865 | 0.88 | TDP1 (0.63) | TDP1LMNAALDH1A1HPGDGAA | |
| Hydrochloric Acid SCHEMBL30395417 | 0.88 | TDP1 (0.63) | TDP1LMNAALDH1A1HPGDGAA | |
| SCHEMBL6414315 | 0.88 | TDP1 (0.63) | TDP1LMNAALDH1A1HPGDGAA | |
| Trifluoromethanesulfonic Acid SCHEMBL3488847 | 0.88 | TDP1 (0.44) | TDP1LMNAALDH1A1HPGDGAA | |
| SCHEMBL1526930 | 0.87 | TDP1 (0.59) | TDP1LMNAALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150359899-A1 | MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS | BOTTI PAOLO (CH) | 2015-12-17 | — | — | US | disclosed |
| US-9211340-B2 | Means and methods of enhancing delivery to biological systems | CAPSUGEL BELGIUM (BE) | 2015-12-15 | — | — | US | disclosed |
| US-9211340-B2 | Means and methods of enhancing delivery to biological systems | CAPSUGEL BELGIUM (BE) | 2015-12-15 | — | — | US | disclosed |
| US-20100062050-A1 | MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS | CAPSUGEL BELGIUM (BE) | 2010-03-11 | — | — | US | disclosed |
| US-20100062050-A1 | MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS | CAPSUGEL BELGIUM (BE) | 2010-03-11 | — | — | US | disclosed |
| WO-2008037463-A2 | MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS | BOTTI PAOLO (CH) | 2008-04-03 | — | — | WO | disclosed |
| US-20050249692-A1 | Polymer, cosmetic composition comprising same and method of preparing same | MITSUBISHI CHEMICAL CORPORATION | 2005-11-10 | — | — | US | disclosed |
| EP-1462463-A1 | Guanidin-group containing polymer, cosmetic employing same and method of preparing same | Mitsubishi Chemical Corporation (JP) | 2004-09-29 | — | — | EP | disclosed |
| EP-0805674-B1 | SKIN AND HAIR COSMETIC COMPOSITIONS | KAO CORP (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-20020172655-A1 | Cosmetic-use polymer, cosmetic employing same, and method of preparing same | MITSUBISHI CHEMICAL CORPORATION | 2002-11-21 | — | — | US | disclosed |
| EP-1236744-A2 | Guanidin-group containing polymer, cosmetic employing same and method of preparing same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6348200-B1 | OXYALKYLAMIDE OR AMINE DERIVATIVES;AT LEAST ONE OF POLYHYDRIC ALCOHOLS, OR VEGETABLE EXTRACTS, OR ORGANIC ACIDS; IMPROVES WATER-RETAINING ABILITY OF HORNY LAYER, CURES ROUGHNESS AND PREVENTS WRINKLES | KAO CORPORATION (JP) | 2002-02-19 | — | — | US | disclosed |
| US-6187955-B1 | A MOISTURIZER FOR SOFTENING SKINS; USEFUL AS COMPONENTS OF COSMETIC FORMULATIONS | KAO CORPORATION (JP) | 2001-02-13 | — | — | US | disclosed |
| US-5723133-A | GUANIDINE WITH ORGANIC ACID FOR SKIN SOFTENING | KAO CORPORATION (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0805674-A1 | SKIN AND HAIR COSMETIC COMPOSITIONS | Kao Corporation (JP) | 1997-11-12 | — | — | EP | disclosed |
| WO-1997014401-A1 | SKIN AND HAIR COSMETIC COMPOSITIONS | KAO CORPORATION (JP) | 1997-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100062050-A1 | MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS | SGTA, GHRHR, IL36G | TDP1 2906/4885LMNA 3031/4885ALDH1A1 1259/4885 |
| US-20150359899-A1 | MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS | PTMS, HGFAC, SLC43A1 | TDP1 2984/4885LMNA 1616/4885ALDH1A1 1096/4885 |
| US-20020172655-A1 | Cosmetic-use polymer, cosmetic employing same, and method of preparing same | DNMT1, PRMT1, JMJD6 | TDP1 369/4885LMNA 1665/4885ALDH1A1 537/4885 |
| US-20050249692-A1 | Polymer, cosmetic composition comprising same and method of preparing same | DNMT1, TET2, H1-0 | TDP1 669/4885LMNA 743/4885ALDH1A1 1198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.