Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | HTR1D | P28221 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3622094 | 0.81 | HTR1D (0.57) | CYP2C19CYP2C9CYP2D6CYP1A2HTR1D | |
| SCHEMBL1159884 | 0.79 | ALDH1A1 (0.41) | CYP2C19CYP2C9CYP2D6CYP1A2HTR1D | |
| SCHEMBL29450175 | 0.79 | ALDH1A1 (0.41) | CYP2C19CYP2C9CYP2D6CYP1A2HTR1D | |
| Hydrochloric Acid SCHEMBL3624760 | 0.78 | ALDH1A1 (0.40) | CYP2C19CYP2C9CYP2D6CYP1A2HTR1D | |
| SCHEMBL11408942 | 0.74 | CYP2C19 (0.65) | HIF1ACYP2C19CYP2C9CYP2D6CYP1A2 | |
| SCHEMBL68929 | 0.74 | ALOX15 (0.58) | HIF1ACYP2C19CYP2C9CYP2D6CYP1A2 | |
| Hydrochloric Acid SCHEMBL11493232 | 0.73 | CYP2D6 (0.63) | HIF1ACYP2C19CYP2C9CYP2D6CYP1A2 | |
| SCHEMBL3624278 | 0.71 | BACE1 (0.43) | CYP2D6HSD17B10ALDH1A1ALOX15HPGD | |
| SCHEMBL9742888 | 0.71 | ALDH1A1 (0.48) | HIF1ACYP2C19CYP2C9CYP2D6CYP1A2 | |
| SCHEMBL8258400 | 0.71 | ALDH1A1 (0.48) | CYP2C19CYP2D6CYP1A2HTR1DHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050234265-A1 | Aminoalkylphenols, methods of using and making the same | MERCK SHARP & DOHME LLC | 2005-10-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234265-A1 | Aminoalkylphenols, methods of using and making the same | NPEPPS, PHOSPHO1, LNPEP | HIF1A 4209/4885CYP2C19 505/4885CYP2C9 1555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.