Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.49 |
| ▸ | MMP3 | P08254 | 5/20 | 0.49 |
| ▸ | MMP9 | P14780 | 5/20 | 0.49 |
| ▸ | MMP13 | P45452 | 5/20 | 0.49 |
| ▸ | MMP1 | P03956 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6300844 | 0.85 | MMP2 (0.61) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL7893160 | 0.84 | MMP2 (0.61) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL7894228 | 0.84 | MMP2 (0.61) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL7893154 | 0.81 | MMP2 (0.55) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL7554346 | 0.81 | MMP2 (0.57) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL7886287 | 0.79 | MMP2 (0.53) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL17150494 | 0.79 | MMP2 (0.51) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL6292126 | 0.79 | MMP2 (0.64) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL18807161 | 0.78 | KMT2A (0.57) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL7551832 | 0.77 | MMP2 (0.62) | MMP2MMP3MMP9MMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050267102-A1 | Inhibition of matrix metalloproteases by substituted biaryl oxobutyric acids | BAYER PHARMACEUTICALS CORPORATION (US) | 2005-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267102-A1 | Inhibition of matrix metalloproteases by substituted biaryl oxobutyric acids | MMP20, ADAMTS5, MMP10 | MMP2 21/4885MMP3 32/4885MMP9 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.