Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | GSK3B | P49841 | 4/20 | 0.54 |
| ▸ | KDR | P35968 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20742179 | 0.87 | GSK3B (0.52) | HPGDKMT2AMEN1GSK3BKDR | |
| SCHEMBL759984 | 0.87 | HPGD (0.60) | HPGDKMT2AMEN1GSK3BKDR | |
| SCHEMBL5412486 | 0.84 | HPGD (0.54) | HPGDKMT2AMEN1GSK3BKDR | |
| SCHEMBL6409547 | 0.83 | EGFR (0.57) | HPGDKMT2AMEN1GSK3BKDR | |
| SCHEMBL5354432 | 0.81 | MEN1 (0.45) | HPGDKMT2AMEN1GSK3BKDR | |
| SCHEMBL6417988 | 0.76 | GSK3B (0.57) | HPGDKMT2AMEN1GSK3BKDR | |
| SCHEMBL31512156 | 0.73 | HPGD (0.37) | HPGDKMT2AMEN1GSK3BKDR | |
| SCHEMBL5357782 | 0.72 | GABRP (0.54) | HPGDKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL16564212 | 0.72 | ALDH1A1 (0.49) | HPGDKMT2AMEN1GSK3BKDR | |
| SCHEMBL8293575 | 0.72 | GSK3B (1.00) | HPGDKMT2AMEN1GSK3BKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092896-A1 | COMPOUND FOR INHIBITING TYROSINE KINASE ACTIVITY OF DDR2 PROTEIN | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2005-10-06 | — | — | WO | disclosed |