Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | SKP1 | P63208 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 2/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2961094 | 0.75 | ACHE (0.45) | ACHENAMPTPRMT5SLC2A1CKS1B | |
| SCHEMBL5002349 | 0.72 | CHRM2 (0.53) | ACHEMEN1KMT2AGPR119 | |
| SCHEMBL20897769 | 0.69 | HTR3A (0.62) | MGLL | |
| SCHEMBL1946774 | 0.68 | GRM5 (0.64) | ACHE | |
| SCHEMBL24265269 | 0.67 | GPR119 (0.56) | ACHEPRMT5CKS1BSKP1SKP2 | |
| SCHEMBL29574249 | 0.67 | GPR119 (0.56) | ACHEPRMT5CKS1BSKP1SKP2 | |
| SCHEMBL20767890 | 0.67 | NAMPT (0.64) | ACHENAMPTCKS1BSKP1SKP2 | |
| SCHEMBL1842426 | 0.67 | MEN1 (0.61) | ACHEMEN1KMT2AGPR119 | |
| SCHEMBL13217691 | 0.67 | ACHE (0.49) | ACHENAMPTPRMT5SLC2A1CKS1B | |
| SCHEMBL26483101 | 0.67 | ACHE (0.53) | ACHESLC2A1CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1514552-A1 | NOVEL FUSED IMIDAZOLE DERIVATIVE | Eisai Co., Ltd. (JP) | 2005-03-16 | — | — | EP | disclosed |