SCHEMBL6409344

SCHEMBL6409344

O=C1C=C(Nc2ccccc2)c2ccccc2C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 1.00
APAF1 O14727 7/20 1.00
KMT2A Q03164 7/20 1.00
CASP3 P42574 6/20 1.00
SENP8 Q96LD8 6/20 1.00
SENP7 Q9BQF6 6/20 1.00
SENP6 Q9GZR1 6/20 1.00
SMN1; SMN2 Q16637 6/20 1.00
BLM P54132 6/20 1.00
MEN1 O00255 6/20 1.00
L3MBTL1 Q9Y468 5/20 1.00
LMNA P02545 5/20 1.00
HTT P42858 5/20 1.00
RAB9A P51151 5/20 1.00
SAE1 Q9UBE0 3/20 1.00
UBA2 Q9UBT2 3/20 1.00
NPSR1 Q6W5P4 3/20 1.00
NPC1 O15118 2/20 1.00
ATM Q13315 1/20 1.00
TDP2 O95551 6/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30587682 1.00 MAPT (1.00) MAPTAPAF1KMT2ACASP3SENP8
SCHEMBL5541831 0.86 MAPT (1.00) MAPTAPAF1KMT2ACASP3SENP8
SCHEMBL31654022 0.86 MAPT (1.00) MAPTAPAF1KMT2ACASP3SENP8
SCHEMBL29633257 0.85 MAPT (1.00) MAPTAPAF1KMT2ACASP3SENP8
SCHEMBL754259 0.85 MAPT (1.00) MAPTAPAF1KMT2ACASP3SENP8
SCHEMBL28408126 0.83 MAPT (0.96) MAPTAPAF1KMT2ACASP3SENP8
SCHEMBL31238099 0.82 MEN1 (0.78) MAPTAPAF1KMT2ACASP3SENP8
SCHEMBL13187310 0.82 CDC25B (1.00) MAPTAPAF1KMT2ACASP3SENP8
SCHEMBL755665 0.79 MAPT (0.64) MAPTAPAF1KMT2ACASP3SENP8
SCHEMBL5161058 0.79 MAPT (0.64) MAPTAPAF1KMT2ACASP3SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113784943-A Oxygen-containing aminophenol compound and method for preventing polymerization of monomer 埃科莱布美国股份有限公司 2021-12-10 CN claimed
EP-3856792-A1 AMINO-QUINONE ANTIPOLYMERANTS AND METHODS OF USING Ecolab USA, Inc. (US) 2021-08-04 EP claimed
CN-112739725-A Amino quinone anti-polymerization agents and methods of use thereof 埃科莱布美国股份有限公司 2021-04-30 CN claimed
WO-2020223224-A1 OXYGENATED AMINOPHENOL COMPOUNDS AND METHODS FOR PREVENTING MONOMER POLYMERIZATION ECOLAB USA INC. (US) 2020-11-05 WO claimed
US-20200102408-A1 AMINO-QUINONE ANTIPOLYMERANTS AND METHODS OF USING ECOLAB USA INC. 2020-04-02 US claimed
WO-2020068735-A1 AMINO-QUINONE ANTIPOLYMERANTS AND METHODS OF USING ECOLAB USA INC. (US) 2020-04-02 WO claimed
CN-112739725-B Amino quinone anti-polymerization agent and method of use thereof 埃科莱布美国股份有限公司 2023-09-26 CN disclosed
US-11312793-B2 Amino-quinone antipolymerants and methods of using ECOLAB USA INC. (US) 2022-04-26 US disclosed
EP-3856792-A1 AMINO-QUINONE ANTIPOLYMERANTS AND METHODS OF USING Ecolab USA, Inc. (US) 2021-08-04 EP disclosed
CN-112739725-A Amino quinone anti-polymerization agents and methods of use thereof 埃科莱布美国股份有限公司 2021-04-30 CN disclosed
WO-2020068735-A1 AMINO-QUINONE ANTIPOLYMERANTS AND METHODS OF USING ECOLAB USA INC. (US) 2020-04-02 WO disclosed
US-20200102408-A1 AMINO-QUINONE ANTIPOLYMERANTS AND METHODS OF USING ECOLAB USA INC. 2020-04-02 US disclosed
EP-1233937-B1 INHIBITION OF POLYMERIZATION OF UNSATURATED MONOMERS CROMPTON CORP (US) 2005-10-26 EP disclosed
US-6653414-B2 Adding to said monomer an effective amount of a mixture comprising at least one stable hindered nitroxyl compound and one quinone or hydroquinone inbibitor UNIROYAL CHEMICAL COMPANY, INC. 2003-11-25 US disclosed
US-20020037958-A1 Inhibition of polymerization of unsaturated monomers ADDIVANT USA, LLC 2002-03-28 US disclosed