SCHEMBL755665

SCHEMBL755665

O=C1C=C(Nc2ccccc2)C(=O)C=C1Nc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.64
L3MBTL1 Q9Y468 5/20 0.64
ALDH1A1 P00352 5/20 0.64
SMN1; SMN2 Q16637 4/20 0.64
MAPK1 P28482 4/20 0.64
MEN1 O00255 4/20 0.64
KMT2A Q03164 4/20 0.64
CASP3 P42574 4/20 0.64
BLM P54132 4/20 0.64
SENP8 Q96LD8 4/20 0.64
SENP7 Q9BQF6 4/20 0.64
SENP6 Q9GZR1 4/20 0.64
LMNA P02545 3/20 0.64
HTT P42858 3/20 0.64
RAB9A P51151 3/20 0.64
APAF1 O14727 3/20 0.64
NPC1 O15118 2/20 0.64
SAE1 Q9UBE0 2/20 0.64
UBA2 Q9UBT2 2/20 0.64
NFKB1 P19838 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5161058 0.90 MAPT (0.64) MAPTL3MBTL1ALDH1A1SMN1; SMN2MAPK1
SCHEMBL17817052 0.88 MAPT (0.53) MAPTL3MBTL1ALDH1A1SMN1; SMN2MAPK1
SCHEMBL21819038 0.86 MAPT (0.51) MAPTL3MBTL1ALDH1A1SMN1; SMN2MAPK1
SCHEMBL29271698 0.84 MAPT (0.54) MAPTL3MBTL1ALDH1A1SMN1; SMN2MAPK1
SCHEMBL21814658 0.83 IDO1 (0.49) MAPTL3MBTL1ALDH1A1SMN1; SMN2MAPK1
SCHEMBL2037194 0.82 MAPT (0.52) MAPTL3MBTL1ALDH1A1SMN1; SMN2MAPK1
SCHEMBL5509707 0.82 MAPT (0.47) MAPTL3MBTL1ALDH1A1SMN1; SMN2MAPK1
SCHEMBL5509711 0.82 MAPT (0.47) MAPTL3MBTL1ALDH1A1SMN1; SMN2MAPK1
SCHEMBL21814675 0.80 IDO1 (0.46) MAPTL3MBTL1ALDH1A1SMN1; SMN2MAPK1
SCHEMBL6409344 0.79 MAPT (1.00) MAPTL3MBTL1ALDH1A1SMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4419580-B1 METHOD FOR PROMOTING HYDROSILYLATION REACTION TO PREPARE ESTER-FUNCTIONAL SILOXANE OLIGOMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-08-27 EP disclosed
US-12398270-B2 Acrylate-functional branched organosilicon compound, method of preparing same, and copolymer formed therewith DOW SILICONES CORPORATION (US) 2025-08-26 US disclosed
US-12378264-B2 Multifunctional organosilicon compound and related methods, compounds, and compositions DOW SILICONES CORPORATION (US) 2025-08-05 US disclosed
US-12371535-B2 Branched organosilicon compound, method of preparing same, and copolymer formed therewith DOW SILICONES CORPORATION (US) 2025-07-29 US disclosed
EP-4172165-B1 PREPARATION OF MULTIFUNCTIONAL ORGANOSILICON COMPOUNDS DOW SILICONES CORP (US) 2025-07-23 EP disclosed
US-20250136625-A1 PROCESS FOR THE PREPARATION OF ORGANIC SILICON COMPOUNDS BASF SE (DE) 2025-05-01 US disclosed
US-20250136763-A1 SILICONE - VINYLESTER FUNCTIONAL COMPOUNDS AND METHODS FOR THEIR PREPARATION AND USE IN PERSONAL CARE COMPOSITIONS DOW SILICONES CORP (US) 2025-05-01 US disclosed
EP-4508106-A1 SILICONE - VINYLESTER FUNCTIONAL COMPOUNDS AND METHODS FOR THEIR PREPARATION AND USE IN PERSONAL CARE COMPOSITIONS Dow Global Technologies LLC (US) 2025-02-19 EP disclosed
EP-4508054-A1 PREPARATION OF ORGANOSILICON COMPOUNDS WITH VINYLESTER FUNCTIONALITY Dow Global Technologies LLC (US) 2025-02-19 EP disclosed
US-12215117-B2 Method of preparing acryloxy-functional organosilicon compounds DOW SILICONES CORPORATION (US) 2025-02-04 US disclosed
US-5302752-A Acetic acid derivatives and their production ETHYL CORPORATION (US) 1994-04-12 US disclosed
US-5122160-A Denim; vat dyes; redox system MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1992-06-16 US disclosed
EP-0431906-A2 Cotton rope-dyeing methods MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-06-12 EP disclosed
EP-0426333-A2 Acetic acid derivatives and their production ETHYL CORPORATION (US) 1991-05-08 EP disclosed
US-5008425-A Trifluoromethylation of carbonyl compounds ETHYL CORPORATION (US) 1991-04-16 US disclosed
US-4871877-A Gem-disubstituted cyclohexadienones and their production ETHYL CORPORATION (US) 1989-10-03 US disclosed
US-4845258-A Production of gem-disubstituted cyclohexadienones ETHYL CORPORATION (US) 1989-07-04 US disclosed
US-4804774-A Production of gem-disubstituted cyclohexadienones ETHYL CORPORATION (US) 1989-02-14 US disclosed
US-4804772-A Gem-disubstituted cyclohexadienones and their production ETHYL CORPORATION (US) 1989-02-14 US disclosed
US-4804773-A Production of gem-disubstituted cyclohexadienones ETHYL CORPORATION (US) 1989-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12378264-B2 Multifunctional organosilicon compound and related methods, compounds, and compositions MSR1, OXSR1, RIOX2 MAPT 4833/4885L3MBTL1 1801/4885ALDH1A1 1749/4885
US-12215117-B2 Method of preparing acryloxy-functional organosilicon compounds MSMO1, ADH5, ADH1C MAPT 4344/4885L3MBTL1 2595/4885ALDH1A1 117/4885
US-20250136763-A1 SILICONE - VINYLESTER FUNCTIONAL COMPOUNDS AND METHODS FOR THEIR PREPARATION AND USE IN PERSONAL CARE COMPOSITIONS VCL, FANCF, MMS19 MAPT 3871/4885L3MBTL1 1707/4885ALDH1A1 592/4885
US-12371535-B2 Branched organosilicon compound, method of preparing same, and copolymer formed therewith OXSR1, BRS3, OXER1 MAPT 4188/4885L3MBTL1 3959/4885ALDH1A1 2965/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.