Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | CASP3 | P42574 | 4/20 | 0.64 |
| ▸ | BLM | P54132 | 4/20 | 0.64 |
| ▸ | SENP8 | Q96LD8 | 4/20 | 0.64 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.64 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | APAF1 | O14727 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.64 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755665 | 0.90 | MAPT (0.64) | MAPTL3MBTL1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL29633257 | 0.79 | MAPT (1.00) | MAPTL3MBTL1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL17817052 | 0.79 | MAPT (0.53) | MAPTL3MBTL1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL30587682 | 0.79 | MAPT (1.00) | MAPTL3MBTL1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL754259 | 0.79 | MAPT (1.00) | MAPTL3MBTL1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL6409344 | 0.79 | MAPT (1.00) | MAPTL3MBTL1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL2037194 | 0.78 | MAPT (0.52) | MAPTL3MBTL1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL28408126 | 0.78 | MAPT (0.96) | MAPTL3MBTL1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL21819038 | 0.78 | MAPT (0.51) | MAPTL3MBTL1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL9333371 | 0.78 | MAPT (0.61) | MAPTL3MBTL1ALDH1A1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1754514-A1 | Agent and method for colouring keratin fibres | Wella Aktiengesellschaft (DE) | 2007-02-21 | — | — | EP | claimed |
| US-20070000073-A1 | Agent and method for colouring keratin fibres | PROCTER & GAMBLE COMPANY, THE | 2007-01-04 | — | — | US | claimed |
| WO-2006094217-A2 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | THE PROCTER & GAMBLE COMPANY (US) | 2006-09-08 | — | — | WO | claimed |
| US-7070625-B2 | Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives | WELLA AG (DE) | 2006-07-04 | — | — | US | claimed |
| EP-1448540-A1 | AGENT AND METHOD FOR COLORING KERATIN FIBERS CONTAINING 2-BENZOTHIAZOLINONE-HYDRAZONE AND QUINONE DERIVATIVES | Wella Aktiengesellschaft (DE) | 2004-08-25 | — | — | EP | claimed |
| US-20040060124-A1 | Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2004-04-01 | — | — | US | claimed |
| WO-2003042199-A1 | AGENT AND METHOD FOR COLORING KERATIN FIBERS CONTAINING 2-BENZOTHIAZOLINONE-HYDRAZONE AND QUINONE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2003-05-22 | — | — | WO | claimed |
| US-5879411-A | Composition and method for dyeing keratin fibers with o-benzoquinones and amino- or hydroxy-containing compounds | WELLA AG (DE) | 1999-03-09 | — | — | US | claimed |
| EP-0848942-A1 | Composition and method for dyeing keratin fibres | Wella Aktiengesellschaft (DE) | 1998-06-24 | — | — | EP | claimed |
| EP-1754514-A1 | Agent and method for colouring keratin fibres | Wella Aktiengesellschaft (DE) | 2007-02-21 | — | — | EP | disclosed |
| US-20070000073-A1 | Agent and method for colouring keratin fibres | PROCTER & GAMBLE COMPANY, THE | 2007-01-04 | — | — | US | disclosed |
| WO-2006094217-A2 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | THE PROCTER & GAMBLE COMPANY (US) | 2006-09-08 | — | — | WO | disclosed |
| US-7070625-B2 | Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives | WELLA AG (DE) | 2006-07-04 | — | — | US | disclosed |
| EP-1448540-A1 | AGENT AND METHOD FOR COLORING KERATIN FIBERS CONTAINING 2-BENZOTHIAZOLINONE-HYDRAZONE AND QUINONE DERIVATIVES | Wella Aktiengesellschaft (DE) | 2004-08-25 | — | — | EP | disclosed |
| US-20040060124-A1 | Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2004-04-01 | — | — | US | disclosed |
| WO-2003042199-A1 | AGENT AND METHOD FOR COLORING KERATIN FIBERS CONTAINING 2-BENZOTHIAZOLINONE-HYDRAZONE AND QUINONE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2003-05-22 | — | — | WO | disclosed |
| US-5879411-A | Composition and method for dyeing keratin fibers with o-benzoquinones and amino- or hydroxy-containing compounds | WELLA AG (DE) | 1999-03-09 | — | — | US | disclosed |
| EP-0848942-A1 | Composition and method for dyeing keratin fibres | Wella Aktiengesellschaft (DE) | 1998-06-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040060124-A1 | Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives | KRT18, NDUFA1, NDUFA2 | MAPT 1723/4885L3MBTL1 4803/4885ALDH1A1 33/4885 |
| US-20070000073-A1 | Agent and method for colouring keratin fibres | KRT18, CDC73, OAT | MAPT 1013/4885L3MBTL1 4858/4885ALDH1A1 494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.