SCHEMBL640963

SCHEMBL640963

C=C(C)C(=O)N(C)[N+](C)(CCC)CCCS(=O)(=O)O

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Betaine SCHEMBL6384849 0.91 TSHR (0.33) ENPP2
SCHEMBL3890430 0.80 EPHX2 (0.31) ENPP2
SCHEMBL6948923 0.74 BBOX1 (0.33) ENPP2
Water SCHEMBL1913461 0.73 BBOX1 (0.32)
SCHEMBL640964 0.72 TDP1 (0.38) ENPP2
Water SCHEMBL1913464 0.71 TDP1 (0.36) ENPP2
SCHEMBL6553774 0.70 TSHR (0.35) ENPP2
SCHEMBL9165713 0.69 SLC22A1 (0.46) ENPP2
SCHEMBL23794905 0.68 ENPP2 (0.40) ENPP2
SCHEMBL24136312 0.67 APP (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1463767-B1 HIGH MOLECULAR WEIGHT CATIONIC AND ANIONIC POLYMERS COMPRISING ZWITTERIONIC MONOMERS NALCO CO (US) 2008-02-27 EP claimed
EP-1644198-B1 INK JET RECORDING MEDIUM CIBA SC HOLDING AG (CH) 2007-04-25 EP claimed
US-8119753-B2 Silicone hydrogels with amino surface groups BAUSCH & LOMB INCORPORATED (US) 2012-02-21 US disclosed
US-20090103045-A1 SILICONE HYDROGELS WITH AMINO SURFACE GROUPS SALIX PHARMACEUTICALS, INC. 2009-04-23 US disclosed
US-20080002146-A1 BIOCOMPATIBLE, SURFACE MODIFIED MATERIALS BAUSCH & LOMB INCORPORATED 2008-01-03 US disclosed
US-20070132125-A1 Use of a super-cooled fluid in lens processing BAUSCH & LOMB INCORPORATED 2007-06-14 US disclosed
US-20070132121-A1 Method of cleaning molds using super-cooled fluids BAUSCH & LOMB INCORPORATED 2007-06-14 US disclosed
US-7147326-B2 Lens with colored portion and coated surface BAUSCH & LOMB INCORPORATED (US) 2006-12-12 US disclosed
EP-1696975-A1 SURFACE TREATMENT UTILIZING SUPERCRITICAL FLUID BAUSCH & LOMB INCORPORATED (US) 2006-09-06 EP disclosed
US-20060114409-A1 Lens with colored portion and coated surface BAUSCH & LOMB INCORPORATED 2006-06-01 US disclosed
EP-1179190-B1 SURFACE TREATMENT OF MEDICAL DEVICES WITH REACTIVE HYDROPHILIC POLYMERS BAUSCH & LOMB (US) 2006-04-12 EP disclosed
US-20030068433-A1 Method for applying polymeric lens coating BAUSCH & LOMB INCORPORATED 2003-04-10 US disclosed
EP-1268621-A1 SURFACE TREATMENT OF SILICONE MEDICAL DEVICES BAUSCH & LOMB INCORPORATED (US) 2003-01-02 EP disclosed
US-20020120084-A1 Surface treatment of silicone medical devices with reactive hydrophilic polymers VALINT PAUL L (US) 2002-08-29 US disclosed
US-6440571-B1 TO INCREASE ITS BIOCOMPATIBILITY OR HYDROPHILICITY; MEDICAL DEVICES SUCH AS CONTACT LENSES BAUSCH & LOMB INCORPORATED 2002-08-27 US disclosed
US-20020102415-A1 SURFACE TREATMENT OF SILICONE HYDROGEL CONTACT LENSES COMPRISING HYDROPHILIC POLYMER CHAINS ATTACHED TO AN INTERMEDIATE CARBON COATING BAUSCH & LOMB MEXICO, S.A. DE C.V. (MX) 2002-08-01 US disclosed
EP-1179190-A1 SURFACE TREATMENT OF MEDICAL DEVICES WITH REACTIVE HYDROPHILIC POLYMERS BAUSCH & LOMB INCORPORATED (US) 2002-02-13 EP disclosed
WO-2001074932-A1 SURFACE TREATMENT OF SILICONE MEDICAL DEVICES BAUSCH & LOMB INCORPORATED (US) 2001-10-11 WO disclosed
US-6200626-B1 OXIDATIVE PLASMA TREATMENT; PLASMA POLYMERIZATION; GRAFTING WITH AN ETHYLENICALLY UNSATURATED MONOMER BAUSCH & LOMB INCORPORATED 2001-03-13 US disclosed
WO-2000072052-A1 SURFACE TREATMENT OF MEDICAL DEVICES WITH REACTIVE HYDROPHILIC POLYMERS BAUSCH & LOMB INCORPORATED (US) 2000-11-30 WO disclosed