Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948923 | 0.99 | BBOX1 (0.33) | BBOX1 | |
| SCHEMBL640963 | 0.73 | ENPP2 (0.33) | — | |
| SCHEMBL3342370 | 0.72 | APP (0.35) | — | |
| SCHEMBL1888580 | 0.72 | TSHR (0.38) | — | |
| Hydrochloric Acid SCHEMBL4151200 | 0.71 | TSHR (0.40) | — | |
| Water SCHEMBL1913464 | 0.70 | TDP1 (0.36) | BBOX1 | |
| SCHEMBL19220237 | 0.69 | — | — | |
| SCHEMBL640964 | 0.68 | TDP1 (0.38) | BBOX1 | |
| SCHEMBL27455553 | 0.67 | APP (0.31) | — | |
| SCHEMBL24136312 | 0.66 | APP (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030161804-A1 | Self-adhesive cationic or amphoteric free-radical polymers and cosmetic use thereof | L'OREAL (FR) | 2003-08-28 | — | — | US | claimed |
| WO-2013186720-A2 | RINSE-OFF COMPOSITION COMPRISING A PRESSURE-SENSITIVE ADHESIVE COMPOUND IN THE FORM OF BEADS | L'OREAL (FR) | 2013-12-19 | — | — | WO | disclosed |
| WO-2012131070-A2 | USE OF A DEVICE FOR TRANSFERRING AN ANTIPERSPIRANT COSMETIC FILM APPLIED ONTO THE SKIN | L'OREAL (FR) | 2012-10-04 | — | — | WO | disclosed |
| WO-2011073345-A2 | USE OF ONE OR MORE PRESSURE-SENSITIVE ADHESIVE COMPOUNDS AS AGENT FOR THE TREATMENT OF SWEATING IN HUMANS | L'OREAL (FR) | 2011-06-23 | — | — | WO | disclosed |
| US-20030161804-A1 | Self-adhesive cationic or amphoteric free-radical polymers and cosmetic use thereof | L'OREAL (FR) | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030161804-A1 | Self-adhesive cationic or amphoteric free-radical polymers and cosmetic use thereof | PARN, PCNA, F13A1 | BBOX1 1493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.