Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.30 |
| ▸ | BHMT | Q93088 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508790 | 0.89 | BHMT (0.35) | S1PR1S1PR3S1PR4S1PR5BHMT | |
| SCHEMBL6348366 | 0.82 | BHMT (0.37) | S1PR1S1PR3S1PR4S1PR5BHMT | |
| SCHEMBL6354774 | 0.76 | BHMT (0.33) | BHMT | |
| SCHEMBL6527718 | 0.70 | FFAR1 (0.32) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL6354686 | 0.69 | LPAR3 (0.37) | BHMT | |
| SCHEMBL6344059 | 0.69 | GRM4 (0.35) | BHMT | |
| SCHEMBL5974079 | 0.69 | LPAR3 (0.39) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL7157667 | 0.68 | LPAR3 (0.42) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL6518662 | 0.67 | SMPD1 (0.38) | S1PR1S1PR3S1PR4 | |
| SCHEMBL11078140 | 0.67 | LPAR3 (0.47) | S1PR1S1PR3S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050020694-A1 | Sulfide and disulfide compounds and compositions for cholesterol management and related uses | ESPERION THERAPEUTICS, INC. | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020694-A1 | Sulfide and disulfide compounds and compositions for cholesterol management and related uses | GSS, STS, CBS | S1PR1 671/4885S1PR3 1002/4885S1PR4 1110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.