Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LIPC | P11150 | 1/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6408026 | 0.82 | NPC1 (0.50) | SMN1; SMN2ATMRAB9ALMNAALDH1A1 | |
| SCHEMBL6404881 | 0.82 | SLC5A7 (0.59) | SMN1; SMN2ATMEPHX2RAB9AGABRA5 | |
| SCHEMBL6408138 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2ATMEPHX2RAB9ALMNA | |
| SCHEMBL6408017 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2ATMEPHX2RAB9ALMNA | |
| SCHEMBL6407440 | 0.80 | EPHX2 (0.57) | SMN1; SMN2ATMEPHX2RAB9ALMNA | |
| SCHEMBL6409331 | 0.79 | ALDH1A1 (0.57) | SMN1; SMN2LMNAALDH1A1GAAMAPT | |
| SCHEMBL6409950 | 0.78 | RAB9A (0.50) | SMN1; SMN2ATMRAB9ALMNAALDH1A1 | |
| SCHEMBL15470638 | 0.74 | EPHX2 (0.56) | SMN1; SMN2ATMEPHX2RAB9ALMNA | |
| SCHEMBL6403886 | 0.73 | SLC5A7 (0.53) | SMN1; SMN2ATMEPHX2RAB9AMAPT | |
| SCHEMBL9548380 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2ATMEPHX2RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | SMN1; SMN2 4458/4885ATM 1728/4885EPHX2 2961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.