Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2399296 | 0.88 | L3MBTL1 (0.49) | L3MBTL1MAPTALDH1A1RAB9AGAA | |
| SCHEMBL6409465 | 0.81 | ATM (0.37) | L3MBTL1MAPTALDH1A1MEN1LMNA | |
| SCHEMBL1457755 | 0.79 | PDGFRB (0.43) | MAPTALDH1A1RAB9AGAASMN1; SMN2 | |
| SCHEMBL6417412 | 0.79 | ATM (0.51) | L3MBTL1MAPTALDH1A1GAAPOLB | |
| SCHEMBL1457277 | 0.78 | ALDH1A1 (0.49) | ALDH1A1GAAMAPK1POLBMEN1 | |
| SCHEMBL1457551 | 0.78 | ALDH1A1 (0.41) | MAPTALDH1A1GAAMAPK1SMN1; SMN2 | |
| SCHEMBL6410801 | 0.77 | KMT2A (0.48) | L3MBTL1ALDH1A1GAAMAPK1SMN1; SMN2 | |
| SCHEMBL1457496 | 0.76 | ALDH1A1 (0.45) | MAPTALDH1A1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL1457183 | 0.76 | HCRTR1 (0.42) | L3MBTL1MAPTALDH1A1GAAMAPK1 | |
| SCHEMBL1456969 | 0.76 | FKBP1A (0.43) | MAPTALDH1A1RAB9AGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401841-B1 | SUBSTITUTED 1-OXA-2,8-DIAZA-SPIRO 4,5]DEC-2-ENE DERIVATIVES AS MEDICAMENTS FOR THE TREATMENT OF PAIN | GRUENENTHAL GMBH (DE) | 2005-08-24 | — | — | EP | disclosed |